Data Driven Intelligent Diagnostics for Parkinson’s Disease

Dai, Yin; Tang, Zheng; Yang, Wang; Xu, Zian

doi:10.1109/access.2019.2931744

Cited by 29 publications

(20 citation statements)

References 7 publications

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“…Recently, with the developments of new techniques such as convolutional neural network [ 101 ] and transfer learning [ 63 ], deep learning gained significant advances in the computer vision tasks, e.g., ImageNet [ 77 ]. Therefore, most of the studies used different imaging data to diagnose PD, such as MRI ( n = 12) [ 41 , 47 , 54 , 56 , 58 , 66 , 72 , 78 , 82 , 86 , 90 , 95 ] and handwritten images ( n = 9) [ 3 , 19 , 25 , 30 , 69 , 75 , 101 , 102 ], as well as PET and CT imaging ( n = 6) [ 28 , 59 , 67 , 71 , 88 , 90 ] and DaTscan imaging ( n = 4) [ 54 , 76 , 99 , 103 ]. However, CNN and transfer learning techniques were not limited to imaging data; they also learn complex features from voices and signal data [ 29 ].…”

Section: Resultsmentioning

confidence: 99%

“…Furthermore, for imaging dataset including MRI, PET CT, and DaTSCAN were mainly obtained from Parkinson Progression Markers Initiative (PPMI) to train classifier, as seen in [ 20 , 28 , 41 , 47 , 59 , 66 , 67 , 76 , 82 , 86 , 88 , 90 , 94 , 95 ]; hence, among all studies, CNN in [ 20 ] and FNN in [ 28 ] achieved an outstanding result for image classification.…”

Section: Discussionmentioning

confidence: 99%

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The Role of Neural Network for the Detection of Parkinson’s Disease: A Scoping Review

et al. 2021

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Background: Parkinson’s Disease (PD) is a chronic neurodegenerative disorder that has been ranked second after Alzheimer’s disease worldwide. Early diagnosis of PD is crucial to combat against PD to allow patients to deal with it properly. However, there is no medical test(s) available to diagnose PD conclusively. Therefore, computer-aided diagnosis (CAD) systems offered a better solution to make the necessary data-driven decisions and assist the physician. Numerous studies were conducted to propose CAD to diagnose PD in the early stages. No comprehensive reviews have been conducted to summarize the role of AI tools to combat PD. Objective: The study aimed to explore and summarize the applications of neural networks to diagnose PD. Methods: PRISMA Extension for Scoping Reviews (PRISMA-ScR) was followed to conduct this scoping review. To identify the relevant studies, both medical databases (e.g., PubMed) and technical databases (IEEE) were searched. Three reviewers carried out the study selection and extracted the data from the included studies independently. Then, the narrative approach was adopted to synthesis the extracted data. Results: Out of 1061 studies, 91 studies satisfied the eligibility criteria in this review. About half of the included studies have implemented artificial neural networks to diagnose PD. Numerous studies included focused on the freezing of gait (FoG). Biomedical voice and signal datasets were the most commonly used data types to develop and validate these models. However, MRI- and CT-scan images were also utilized in the included studies. Conclusion: Neural networks play an integral and substantial role in combating PD. Many possible applications of neural networks were identified in this review, however, most of them are limited up to research purposes.

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Section: Resultsmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

The Role of Neural Network for the Detection of Parkinson’s Disease: A Scoping Review

et al. 2021

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“…Combining down-sampling ways with up-sampling ways present a U-shape. Inspired by the deformable convolution neural network which was published by Dai in 2019 [26], this work replaces typical convolution kernel with deformable convolution in the whole network. The improved U-Net architecture is shown in Figure 14.…”

Section: Improved Structure Of Deformable U-net (Deu-net)mentioning

confidence: 99%

Computer-Aided Diagnosis of Alzheimer’s Disease via Deep Learning Models and Radiomics Method

et al. 2021

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This paper focused on the problem of diagnosis of Alzheimer’s disease via the combination of deep learning and radiomics methods. We proposed a classification model for Alzheimer’s disease diagnosis based on improved convolution neural network models and image fusion method and compared it with existing network models. We collected 182 patients in the ADNI and PPMI database to classify Alzheimer’s disease, and reached 0.906 AUC in training with single modality images, and 0.941 AUC in training with fusion images. This proved the proposed method has better performance in the fusion images. The research may promote the application of multimodal images in the diagnosis of Alzheimer’s disease. Fusion images dataset based on multi-modality images has higher diagnosis accuracy than single modality images dataset. Deep learning methods and radiomics significantly improve the diagnosing accuracy of Alzheimer’s disease diagnosis.

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“…Hence, the segmentation of the lumen and carotid artery boundaries in bifurcation regions is expected to be considered in future researches. Although Deep Learning approaches have been a topic of research highly discussed and used in many studies related to image segmentation and classification tasks ( [47,48,49,50,51,52,53]), the proposed method presented here is aimed for the identification of structures in medical images by means of well-known image processing and analysis algorithms. However, we also intend to consider Deep Learning techniques for the segmentation of the structures of the carotid arteries in future works.…”

Section: Limitationsmentioning

confidence: 99%

Using a distance map and an active contour model to segment the carotid artery boundary from the lumen contour in proton density weighted magnetic resonance images

Jodas

Costa

Parreira

et al. 2020

Computers in Biology and Medicine

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Segmentation methods have assumed an important role in image-based diagnosis of several cardiovascular diseases. Particularly, the segmentation of the boundary of the carotid artery is demanded in the detection and characterization of atherosclerosis and assessment of the disease progression. In this article, a fully automatic approach for the segmentation of the carotid artery boundary in Proton Density Weighted Magnetic Resonance Images is presented. The approach relies on the expansion of the lumen contour based on a distance map built using the gray-weighted distance relative to the centre of the identified lumen region in the image under analysis. Then, a Snake model with a modified weighted external energy based on the combination of a balloon force along with a Gradient Vector Flow-based external energy is applied to the expanded contour towards the correct boundary of the carotid artery. The average values of the Dice coefficient, Polyline distance, mean contour distance and centroid distance found in the segmentation of 139 carotid arteries were 0.83 ± 0.11, 2.70 ± 1.69 pixels, 2.79 ± 1.89 pixels and 3.44 ± 2.82 pixels, respectively. The segmentation results of the proposed approach were also compared against the ones obtained by related approaches found in the literature, which confirmed the outstanding performance of the new approach. Additionally, the proposed weighted external energy for the Snake model was shown to be also robust to carotid arteries with large thickness and weak boundary image edges.

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Data Driven Intelligent Diagnostics for Parkinson’s Disease

Cited by 29 publications

References 7 publications

The Role of Neural Network for the Detection of Parkinson’s Disease: A Scoping Review

The Role of Neural Network for the Detection of Parkinson’s Disease: A Scoping Review

Computer-Aided Diagnosis of Alzheimer’s Disease via Deep Learning Models and Radiomics Method

Using a distance map and an active contour model to segment the carotid artery boundary from the lumen contour in proton density weighted magnetic resonance images

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