Data mining-based analysis on medication rules of Chinese herbal medicine treating headache with blood stasis syndrome

Liu, Guanghui; Yang, Haijun; Li, Bai; Wang, Yan; Wang, En-long; Sun, Xiu-ye; Zhang, Hongyuan; Li, Zhou; Zhang, Zhe

doi:10.1016/j.heliyon.2023.e14996

Cited by 2 publications

(2 citation statements)

References 20 publications

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“…Employing traditional Chinese remedies known for activating blood stasis, for instance, Tao Hong Si Wu Tang, and Qi Tonifying and Tongluo Granules, enables researchers to effectively alleviate alterations in hemodynamics and blood rheology, mitigate platelet activation and aggregation, and notably enhance blood circulation. By using traditional Chinese medicines that activate blood stasis, such as Tao Hong Si Wu Tang, and Qi Tonifying and Tongluo Granules, researchers can effectively improve hemodynamics and blood rheology, reduce platelet activation and aggregation, and enhance blood circulation ( 92 – 95 ). This can help prevent and treat atherosclerosis.…”

Section: Discussionmentioning

confidence: 99%

Exploring global research trends in Chinese medicine for atherosclerosis: a bibliometric study 2012–2023

Tan,

Wang,

Chen

et al. 2024

Front. Cardiovasc. Med.

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BackgroundWhile Traditional Chinese Medicine (TCM) boasts an extensive historical lineage and abundant clinical expertise in addressing atherosclerosis, this field is yet to be penetrated adequately by bibliometric studies. This study is envisaged to evaluate the contemporary scenario of TCM in conjunction with atherosclerosis over the preceding decade while also identifying forthcoming research trends and emerging topics via the lens of bibliometric analysis.MethodsLiterature pertaining to TCM and atherosclerosis, circulated between January 1, 2012 and November 14, 2023, was garnered for the purpose of this research. The examination embraced annual publications, primary countries/regions, engaged institutions and authors, scholarly journals, references, and keywords, utilizing analytical tools like Bibliometrix, CiteSpace, ScimagoGraphica, and VOSviewer present in the R package.ResultThis field boasts a total of 1,623 scholarly articles, the majority of which have been contributed by China in this field, with significant contributions stemming from the China Academy of Traditional Chinese Medicine and the Beijing University of Traditional Chinese Medicine. Moreover, this field has received financial support from both the National Natural Science Foundation of China and the National Key Basic Research Development Program. Wang Yong tops the list in terms of publication count, while Xu Hao's articles take the lead for the total number of citations, positioning them at the core of the authors’ collaborative network. The Journal of Ethnopharmacology leads with the most publications and boasts the greatest total number of citations. Principal research foci within the intersection of Chinese Medicine and Atherosclerosis encompass disease characteristics and pathogenic mechanisms, theoretical underpinnings and syndrome-specific treatments in Chinese medicine, potentialities of herbal interventions, and modulation exerted by Chinese medicines on gut microbiota.ConclusionThis analysis offers a sweeping survey of the contemporary condition, principal foci, and progressive trends in worldwide research related to Traditional Chinese Medicine (TCM) and atherosclerosis. It further delves into an in-depth dissection of prominent countries, research institutions, and scholars that have made noteworthy strides in this discipline. Additionally, the report analyzes the most cited articles, research developments, and hotspots in the field, providing a reference for future research directions for clinical researchers and practitioners.

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Section: Discussionmentioning

confidence: 99%

Exploring global research trends in Chinese medicine for atherosclerosis: a bibliometric study 2012–2023

Tan,

Wang,

Chen

et al. 2024

Front. Cardiovasc. Med.

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“…25 In contemporary medical and clinical research, the underlying pathology of headaches associated with blood stasis syndrome involves abnormalities in microcirculation, characterized by irregularities in hemorheology, hemodynamics, and the formation of scar tissue. 26 Hence, the treatment approach for headache characterized by blood stasis syndrome continues to focus on promoting blood circulation and resolving stasis.…”

Section: Introductionmentioning

confidence: 99%

Acupoints for Headache with Blood Stasis Syndrome: a Literature Study Based on Data Mining Technology

Shi,

Li,

Yang

et al. 2024

JPR

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Objective This study aimed to investigate the features and underlying principles of acupuncture points used in the treatment of headaches associated with blood stasis syndrome. Methods Literature on the treatment of blood stasis headache with acupuncture and moxibustion was searched across three Chinese databases and one English database from January 1st, 2000, to January 1st, 2024. Relevant data including titles, journals, authors, keywords, interventions, main acupoints, and outcomes were extracted for further analysis. Results A total of 112 papers with 102 complete prescriptions were analyzed. Of the 77 acupoints examined, 72 were meridian points, and 5 were extraordinary points, used 699 times in total. The top ten acupoints by frequency were Fengchi (GB20), Taiyang (EX-HN5), Baihui (GV20), Hegu (LI4), Shuaigu (GB8), Taichong (LR3), Xuehai (SP10), Touwei (ST8), Geshu (BL17), and Waiguan (TE5). Yang meridian points were used more frequently than Yin meridian points (82.8% vs 17.2%), with the Gallbladder Meridian of Foot Shaoyang being the most common. Nearly half of the acupoints (49.9%) were on the head and neck, and 23.1% on the lower limbs. Specific acupoints accounted for 53.5% of the total frequency. Fengchi (GB20) and Taiyang (EX-HN5) showed the highest correlation. Association rule mining highlighted combinations like Fengchi (GB20) with Taiyang (EX-HN5) and Baihui (GV20). Cluster analysis yielded five clusters. Conclusion The study provides insights into selecting effective acupoints and combinations for clinical acupuncture practice and experimental studies in treating blood stasis headaches. Acupoints like Fengchi (GB20), Taiyang (EX-HN5), and Baihui (GV20) may be effective for clinical treatment, but further studies are needed to validate their efficacy.

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Data mining-based analysis on medication rules of Chinese herbal medicine treating headache with blood stasis syndrome

Cited by 2 publications

References 20 publications

Exploring global research trends in Chinese medicine for atherosclerosis: a bibliometric study 2012–2023

Exploring global research trends in Chinese medicine for atherosclerosis: a bibliometric study 2012–2023

Acupoints for Headache with Blood Stasis Syndrome: a Literature Study Based on Data Mining Technology

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