Daytime Functional Bladder Capacity as a Predictor of Response to Desmopressin in Monosymptomatic Nocturnal Enuresis

Eller, Douglas A.; Austin, Paul F.; Tanguay, Simon; Homsy, Yves

doi:10.1159/000052238

Cited by 60 publications

(52 citation statements)

References 7 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…That those with no or a partial response had more wet nights during the observation period also suggests other factors than polyuria in nocturnal enuresis. Thus the present results con®rm earlier reports, that a good response to desmopressin is associated with increasing age and fewer initial wet nights [7,14].…”

Section: Discussionsupporting

confidence: 92%

“…bladder dysfunction and/or arousal problems, are responsible for the enuresis. This also supports the idea of functional bladder capacity as an important factor for nocturnal enuresis, and a reduction of bladder capacity as a prognostic factor for reduced response to desmopressin [7]. In a Japanese study with overnight simultaneous monitoring by EEG and cystometry, three types of enuresis were classi®ed.…”

Section: Discussionsupporting

confidence: 69%

“…Besides nocturnal polyuria, bladder capacity [7] in¯u-ences the outcome of treatment, but other factors are less well known. A response to desmopressin was associated with a positive family history of nocturnal enuresis in one study [8], but not in another [9].…”

Section: Introductionmentioning

confidence: 99%

See 2 more Smart Citations

Treatment of primary monosymptomatic nocturnal enuresis with desmopressin: predictive factors

et al. 2001

View full text Add to dashboard Cite

On behalf of the Swedish Enuresis Trial (SWEET) Group (see Appendix) Objective To investigate predictive factors for the outcome of treatment of primary monosymptomatic nocturnal enuresis (PMNE) with desmopressin. Patients and methods Data from a large open multicentre study were analysed. The study comprised 399 children with PMNE who were recruited for long-term desmopressin treatment. Before treatment a history was taken and the children observed for 4 weeks. After a 6-week dose-titration period with desmopressin, the children were classi®ed into four groups depending on the response rate. Results The children who improved during desmopressin treatment were older, had fewer wet nights during the observation period and had only one wet episode during the night, mostly after midnight. Many of them did not require the maximum dose of desmopressin to become dry. No hereditary factor for the response to desmopressin was found. Conclusion Those most likely to be permanently dry with desmopressin treatment are older children who respond to 20 mg desmopressin and who do not wet frequently.

show abstract

Section: Discussionsupporting

confidence: 92%

Section: Discussionsupporting

confidence: 69%

See 1 more Smart Citation

Treatment of primary monosymptomatic nocturnal enuresis with desmopressin: predictive factors

et al. 2001

View full text Add to dashboard Cite

show abstract

“…Biofeedback therapy has been determined to be useful both as a musculoskeletal and neurological treatment modality. [6] Eller et al [15] reported the mean FBC in children with MsE was only 63% of that of normal children. In their reports, children with nocturnal enuresis, who were proven to have reduced bladder capacity, were less likely to respond to desmopressin treatment.…”

Section: Discussionmentioning

confidence: 98%

The effectiveness of biofeedback therapy in children with monosymptomatic enuresis resistant to desmopressin treatment

Sancak

Akbaş

Kurt

et al. 2016

Turkish Journal of Urology

View full text Add to dashboard Cite

Objective: To investigate the effect of biofeedback therapy on children with desmopressin-resistant primary monosymptomatic enuresis (MsE). Material and methods:The study comprised both retrospective and prospective sections. A total of 262 medical files of patients who were diagnosed as enuresis between November 2012 and January 2015 were retrospectively screened. Patients with neuropathic bladder, daytime voiding problems, anatomical pathology and enuresis-related diseases were excluded from the study. The demographic data and family characteristics of 29 children with desmopressin-resistantprimary MsE were recorded. After biofeedback treatment patients whose frequency of enuretic episodes decrease by more than 50% were included in the successful biofeedback treatment group (SBTG), while other patients were categorized in the unsuccessful biofeedback treatment group (USGBT). The outcomes of uroflowmetry, voided volume, postvoiding residue (PVR) and total bladder volume/age-adjusted normal bladder capacity (TBV/NBC) were recorded before and at the sixth month of the treatment.

show abstract

“…One of the treatment challenges in the management of enuresis is predicting which patients will respond to desmopressin. EBC has been demonstrated to be a reliable predictor of response to desmopressin; children with larger capacities are more likely to exhibit a successful response [12][13][14].…”

mentioning

confidence: 99%

New directions for the endocrine treatment of bedwetting

Austin

2009

Expert Review of Endocrinology & Metabolism

View full text Add to dashboard Cite

Daytime Functional Bladder Capacity as a Predictor of Response to Desmopressin in Monosymptomatic Nocturnal Enuresis

Cited by 60 publications

References 7 publications

Treatment of primary monosymptomatic nocturnal enuresis with desmopressin: predictive factors

Treatment of primary monosymptomatic nocturnal enuresis with desmopressin: predictive factors

The effectiveness of biofeedback therapy in children with monosymptomatic enuresis resistant to desmopressin treatment

New directions for the endocrine treatment of bedwetting

Contact Info

Product

Resources

About