Daytime naps and depression risk: A meta-analysis of observational studies

Li, Liqing; Zhang, Qi; Zhu, Liyong; Zeng, Guohua; Huang, Hongwei; Zhuge, Jian; Kuang, Xiaorui; Yang, Sule; Yang, Di; Chen, Zhensheng; Gan, Yong; Lu, Zuxun; Wu, Chunmei

doi:10.3389/fpsyg.2022.1051128

Cited by 9 publications

(1 citation statement)

References 93 publications

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“…Regardless of the length of sleep, siesta is related to diabetes, obesity, epidemic stroke and myocardial infarction in elderly women ( 27 ). Regarding the relationship between napping and depression, studies have shown that nappers are slightly more likely to suffer from depression than non nappers, and daytime napping may be a secondary result or symptom of poor health and sleep disorders, which may be an independent risk factor for depression ( 44 ). In addition, an MR analysis study on identifying modifiable factors for preventing depression found that the trend of daytime napping in adults seems to increase the risk of depression ( 45 ), especially when napping for more than an hour ( 46 ).…”

Section: Discussionmentioning

confidence: 99%

Depression and hepatobiliary diseases: a bidirectional Mendelian randomization study

Kong,

Yao,

Ren

et al. 2024

Front. Psychiatry

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BackgroundMore and more evidence suggests a close association between depression and hepatobiliary diseases, but its causal relationship is not yet clear.MethodUsing genome-wide association studies (GWAS) to summarize data, independent genetic variations associated with depression were selected as instrumental variables. Firstly, we designed a univariate Mendelian randomization (UVMR) analysis with two samples and simultaneously conducted reverse validation to evaluate the potential bidirectional causal relationship between depression and various hepatobiliary diseases. Secondly, we conducted a multivariate Mendelian randomization (MVMR) analysis on diseases closely related to depression, exploring the mediating effects of waist to hip ratio, hypertension, and daytime nap. The mediating effects were obtained through MVMR. For UVMR and MVMR, inverse variance weighted method (IVW) is considered the most important analytical method. Sensitivity analysis was conducted using Cochran’Q, MR Egger, and Leave-one-out methods.ResultsUVMR analysis showed that depression may increase the risk of non-alcoholic fatty liver disease (OR, 1.22; 95% CI, 1.03-1.46; p=0.0248) in liver diseases, while depression does not increase the risk of other liver diseases; In biliary and pancreatic related diseases, depression may increase the risk of cholelithiasis (OR, 1.26; 95% CI, 1.05-1.50; p=0.0120), chronic pancreatitis (OR, 1.61; 95% CI, 1.10-2.35; p=0.0140), and cholecystitis (OR, 1.23; 95% CI, 1.03-1.48; p=0.0250). In addition, through reverse validation, we found that non-alcoholic fatty liver disease, cholelithiasis, chronic pancreatitis, cholecystitis, or the inability to increase the risk of depression (p>0.05). The waist to hip ratio, hypertension, and daytime nap play a certain role in the process of depression leading to non-alcoholic fatty liver disease, with a mediating effect of 35.8%.ConclusionDepression is a susceptibility factor for non-alcoholic fatty liver disease, and the causal effect of genetic susceptibility to depression on non-alcoholic fatty liver disease is mediated by waist-hip ratio, hypertension, and daytime nap.

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Section: Discussionmentioning

confidence: 99%

Depression and hepatobiliary diseases: a bidirectional Mendelian randomization study

Kong,

Yao,

Ren

et al. 2024

Front. Psychiatry

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Prevalence and associated factors of napping among older adults in the Philippines

Pengpid,

Peltzer

2024

Sleep Breath

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Background The aim of the study is to estimate the prevalence and associated factors of insomnia among older adults in the Philippines. Methods In all, 5206 cross-sectional nationally representative data from older adults (≥ 60 years) of the 2018 Longitudinal Study on Ageing and Health in the Philippines (LSAHP) was analysed. Napping frequency and duration were assessed by self-report. Results The prevalence of regular nappers was 35.7%, low or moderate napping (1–59 min) was 10.5% and long napping (≥ 60 min) duration was 25.2%. In the final adjusted model, older age was not significantly associated with low or moderate napping duration but older age was positively associated with long napping duration. High wealth status, physical activity and late insomnia were positively associated with low or moderate napping duration. High wealth status, urban residence, daily activity limitations, and physical activity were positively associated, and currently working status, poor self-rated health status and current alcohol use were negatively associated with long napping duration. Conclusion One in four older adults reported long napping duration. Sociodemographic, health status and behaviour and sleep parameters were associated with low or moderate and/or long napping duration.

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Daytime napping and depressive symptoms in bipolar disorder: A cross-sectional analysis of the APPLE cohort

Esaki,

Obayashi,

Saeki

et al. 2024

Sleep Medicine

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Daytime naps and depression risk: A meta-analysis of observational studies

Cited by 9 publications

References 93 publications

Depression and hepatobiliary diseases: a bidirectional Mendelian randomization study

Depression and hepatobiliary diseases: a bidirectional Mendelian randomization study

Prevalence and associated factors of napping among older adults in the Philippines

Daytime napping and depressive symptoms in bipolar disorder: A cross-sectional analysis of the APPLE cohort

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