2020
DOI: 10.21203/rs.3.rs-34260/v1
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Daytime sleepiness, night sleep changes and ALS: a Mendelian randomization study

Abstract: Background Observational studies have indicated that there is a high prevalence of daytime sleepiness and night sleep changes in amyotrophic lateral sclerosis (ALS). However, the actual relation between these symptoms and ALS remains unclear. We aimed to determine whether daytime sleepiness and night sleep changes have an effect on ALS. Methods We used 2-sample mendelian randomization to estimate the effects of daytime sleepiness, sleep efficiency, number of sleep episodes and sleep duration on ALS. Summary … Show more

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References 39 publications
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