De Gustibus: time scale of loss and recovery of tastes caused by radiotherapy

Maes, André; Huygh, I.; Weltens, Caroline; Vandevelde, G.; Delaere, Pierre; Evers, Georges; Bogaert, Walter Van den

doi:10.1016/s0167-8140(02)00025-7

Cited by 106 publications

(96 citation statements)

References 23 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…This is followed by general abnormal taste and a reduction in taste acuity. 199,201,207,[209][210][211][212][213] Umami declines during the third week of RT. After RT, taste sensitivity usually recovers within several months after the resolution of mucosal damage.…”

Section: Taste Alterations In Cancermentioning

confidence: 99%

Oral complications of cancer and cancer therapy

Epstein

Thariat

Bensadoun

et al. 2012

CA A Cancer J Clinicians

431

356

View full text Add to dashboard Cite

Answer questions and earn CME/CNEOral complications resulting from cancer and cancer therapies cause acute and late toxicities that may be underreported, underrecognized, and undertreated. Recent advances in cancer treatment have led to changes in the incidence, nature, and severity of oral complications. As the number of survivors increases, it is becoming increasingly recognized that the aggressive management of oral toxicities is needed to ensure optimal long‐term oral health and general well‐being. Advances in care have had an impact on previously recognized oral complications and are leading to newly recognized adverse effects. Here, the authors briefly review advances in cancer therapy, including recent advances in surgery, oral care, radiation therapy, hematopoietic cell transplantation, and medical oncology; describe how these advances affect oral health; and discuss the frequent and/or severe oral health complications associated with cancer and cancer treatment and their effect upon long‐term health. Although some of the acute oral toxicities of cancer therapies may be reduced, they remain essentially unavoidable. The significant impact of long‐term complications requires increased awareness and recognition to promote prevention and appropriate intervention. It is therefore important for the primary oncologist to be aware of these complications so that appropriate measures can be implemented in a timely manner. Prevention and management is best provided via multidisciplinary health care teams, which must be integrated and communicate effectively in order to provide the best patient care in a coordinated manner at the appropriate time. CA Cancer J Clin 2012. © 2012 American Cancer Society.

show abstract

Section: Taste Alterations In Cancermentioning

confidence: 99%

Oral complications of cancer and cancer therapy

Epstein

Thariat

Bensadoun

et al. 2012

CA A Cancer J Clinicians

431

356

View full text Add to dashboard Cite

show abstract

“…DeWys & Walters (1975) have suggested that ‡ 50% of patients with cancer have impaired taste functioning at some point during the course of their disease and treatment. The duration of losses can last from several weeks to 6 months, or longer (Conger, 1973;Mossman & Henkin, 1978;Ophir et al 1988;Maes et al 2002;Schiffman et al 2007). Altered taste perception in cancer can be caused by metabolic changes induced by the presence of a neoplasm as well as damage to the sensory receptors by radiotherapy and chemotherapy.…”

Section: Critical Illnessmentioning

confidence: 99%

Critical illness and changes in sensory perception

Schiffman

2007

Proc. Nutr. Soc.

View full text Add to dashboard Cite

Impairments of sensory perception that occur during a period of critical care can seriously impact on health and nutritional status, activities of daily living, independence, quality of life and the possibility of recovery. It is emphasized from the outset that sensory losses in criticallyill patients may or may not be related to their current medical condition. The present paper provides an overview of all five senses (vision, hearing, taste, smell and touch) and describes the factors that contribute to sensory losses in critically-ill patients, including medications, medical conditions and treatments and the process of aging itself. Cancer and stroke are two critical illnesses in which profound sensory decrements often occur. Many sensory complaints in patients with cancer are related to alteration in sensory signals caused by damage to the sensory receptors. However, some complaints, such as taste aversions in patients with cancer, are not related to altered sensory physiology per se but to learned aversions that arise during the noxious effects of radiotherapy and chemotherapy. The paper also reviews a study in which the sensory performance (of all five senses) was compared in three groups of elderly subjects: (1) patients who had undergone coronary artery bypass surgery; (2) patients with cardiovascular conditions but with no history of surgery; (3) healthy non-medicated age-matched controls. Performance of patients who had undergone coronary artery bypass surgery was worse than that for the other two groups, with taste and smell losses greater than for the other senses. The study demonstrates that critical illness (e.g. coronary artery bypass surgery) can exacerbate sensory losses in an older cohort.

show abstract

“…Several published studies have examined the influence of cancer treatment on the sense of taste by measuring taste in this way [13][14][15][16][17][18]. The authors state in their methodology that, "Dysgeusia was assessed by the presence (Y/N) or grade when available."…”

mentioning

confidence: 99%