De Novo AL Amyloidosis in a Renal Allograft

Hwang, Jeoung Yeon; Lee, Dong Ryeol; An, Jung Myung; Kim, Sung Jun; Kim, Dong Kyu; Park, Min Gi; Park, Su Ho

doi:10.3904/kjm.2016.90.6.545

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2020

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“…In all cases, immunohistochemical staining of graft renal biopsy showed positive findings of congo red and lambda light chain. In Korea, newly diagnosed AL amyloidosis after renal transplantation is known only one case in 2016 by Hwang et al ( Table 1 ) [ 9 ].…”

Section: Discussionmentioning

confidence: 99%

Amyloid light-chain amyloidosis presented as focal segmental glomerulosclerosis in a kidney transplant recipient

Park

Kwon

Lee

et al. 2020

Korean J Transplant

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Amyloid light-chain (AL) amyloidosis after kidney transplantation is a rare disease in the world, and only one case of systemic AL amyloidosis after kidney transplantation is reported in Korea. We here report a 46-year-old woman with AL amyloidosis developed after kidney transplantation. The underlying disease of our case was focal segmental glomerulosclerosis (FSGS), and was admitted to hospital for evaluation of proteinuria developed 2 years after kidney transplantation. The patient was initially diagnosed as recurrent FSGS on light microscopy. But, electron microscopic finding was suggestive of amyloidosis and systemic evaluation was consistent with systemic AL amyloidosis. This case provides the importance of differential diagnosis of proteinuria in kidney transplant recipients.

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Section: Discussionmentioning

confidence: 99%