De Novo Oligometastatic Breast Cancer

Abstract

De novo oligometastatic breast cancer, a unique disease needing new treatment paradigms.

Accumulation of CD56+ CD16- Natural Killer Cells in Response to Preoperative Chemotherapy for Breast Cancer

“…Five patients in this study had de-novo stage-IV (metastatic) disease. Clinical and molecular analyses have shown that metastatic disease often shares molecular similarities with primary tumors [ 31 ], and four of these patients had G ≥ 2 therapeutic responses, which can be explained by the activation of NK-mediated antitumor immunity.…”