2015
DOI: 10.1016/j.biopha.2014.11.020
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Deacetyl-mycoepoxydiene, isolated from plant endophytic fungi Phomosis sp. demonstrates anti-microtubule activity in MCF-7 cells

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Cited by 6 publications
(1 citation statement)
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“…Similar to other reports, mycoepoxydiene was found active against human breast cancer MCF-7 (IC 50 9.27 μM) and human oral cavity cancer KB (IC 50 14.43 μM) cells while the rest were less active [ 7 , 12 ]. Based on the cytotoxic mechanisms of mycoepoxydiene derivatives, they are able to induce cancer cells apoptosis in vivo , thus reflecting their potential for the development of anti-cancer drugs [ 13 ].…”
Section: Mycoepoxydienesmentioning
confidence: 99%
“…Similar to other reports, mycoepoxydiene was found active against human breast cancer MCF-7 (IC 50 9.27 μM) and human oral cavity cancer KB (IC 50 14.43 μM) cells while the rest were less active [ 7 , 12 ]. Based on the cytotoxic mechanisms of mycoepoxydiene derivatives, they are able to induce cancer cells apoptosis in vivo , thus reflecting their potential for the development of anti-cancer drugs [ 13 ].…”
Section: Mycoepoxydienesmentioning
confidence: 99%