Dead sea climatotherapy for psoriasis vulgaris: analysis of short-term results

Harari, Marco; Sela, Yaron; Ingber, Arieh; Vardy, Daniel

doi:10.15761/god.1000177

Cited by 6 publications

(9 citation statements)

References 8 publications

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“… Harari et al, 2007 [ 77 ] DSC Prospective, single-arm cohort 4 w 64 42M/22F 41.4 16.8 y N/A PASI, QoL VAS All subjects attained PASI 50, and 75.9% of cases reached PASI 75 after 1 mo of DSC, with a median remission length of 23.1 w and median therapeutic effect duration of 33.6 w. Younger patient age at therapy was correlated with a longer remission time. Harari et al, 2016 [ 78 ] DSC Retrospective report 3–4 w 719 505M/214F 51.24 28.01 y N/A PASI, BMI, body surface involvement Previous DSC sessions were a positive predictor for an improved PASI, with a positive association between psoriasis duration (and younger age at onset) and PASI 90. More patients with photo skin type II (Fitzpatrick) achieved PASI 90 than other types.…”

Section: Resultsmentioning

confidence: 99%

“…Balneotherapy and Climatotherapy denote already established CAM treatment methods in moderate-to-severe psoriasis, having been proven effective in the short-term clearing and remission induction across several studies [ 18 , 70 , 110 , 111 ]. The most common destination for climate therapy is the Dead Sea, with 18 out of the total of 34 studies included having been conducted there [ 17 , 18 , 25 , 70 , 71 , 72 , 73 , 74 , 75 , 76 , 77 , 78 , 79 , 80 , 81 , 82 , 83 , 84 ]. This treatment method implies spending several weeks at the Dead Sea, bathing in its waters and lying in the sun.…”

Section: Discussionmentioning

confidence: 99%

“…Furthermore, some of these studies also showed an improved quality of life, as measured by DLQI [ 72 , 84 ]. Both Kushelevski and Harari reported a higher clearance rate of lesions in patients with early-onset psoriasis and those with a longer duration of the disease [ 76 , 77 , 78 , 81 ]. Currently, the influence of the number of previous climate therapy stays on clinical amelioration has not been definitively established [ 78 , 84 ].…”

Section: Discussionmentioning

confidence: 99%

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Mind-Body Interventions as Alternative and Complementary Therapies for Psoriasis: A Systematic Review of the English Literature

2021

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Objective: Conventional therapeutic methods for psoriasis include topical and systemic drugs, phototherapy, and biologic agents. Despite the fact that these treatment methods, and especially biologic agents, are met with a considerable reduction in disease activity, they can sometimes be costly and are nonetheless accompanied by high risks of adverse events, ranging from mild to debilitating. Therefore, complementary and alternative medicine (CAM), especially mind-and-body interventions, such as acupuncture, psychotherapy, climatotherapy, and cupping may provide a cheaper and potentially beneficial outcome for these patients. Methods: We performed a systematic review of articles pertaining to acupuncture, cupping, psychotherapy and meditation, as well climatotherapy and balneotherapy in the management of psoriasis, by using the PubMED, Medline and Google Academic research databases and reference cross-checking. Results: 12 articles on acupuncture, 9 on dry or wet cupping, 27 concerning meditation, hypnosis or psychotherapy, and 34 regarding climate therapy or balneotherapy were found. Discussion and Conclusions: Currently, there is a lack of evidence in the English literature to support acupuncture as an effective alternative therapy for psoriasis, whereas cupping has been described in the majority of instances to result in Koebner phenomenon and clinical worsening. Stress management therapies such as psychotherapy, hypnosis, and meditation have shown promising results as complementary treatment methods. Climatotherapy and balneotherapy have already been proven as effective means of achieving clinical improvement in psoriasis. Further research is still needed to verify the usefulness of the lesser studied treatment methods.

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Section: Resultsmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

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Mind-Body Interventions as Alternative and Complementary Therapies for Psoriasis: A Systematic Review of the English Literature

2021

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“…For many decades, Dead Sea, which is known as natural source of minerals, sea salts and seaweeds, has represented beneficial effects on skin care particularly in treatment of psoriasis. 1 Seaweeds are one of the multiple marine organisms with different derivative compounds and have been used widely in pharmaceutical and cosmeceutical industry. Diverse constitutes produced by algae comprise primary metabolites like proteins, polysaccharides, fatty acids and amino acids.…”

Section: Introductionmentioning

confidence: 99%

Comparative evaluation of Gracilaria algae 3% cream vs Clobetasol 0.05% cream in treatment of plaque type psoriasis: A randomized, split‐body, triple‐blinded clinical trial

Shatalebi

Jazi

Yegdaneh

et al. 2020

Dermatologic Therapy

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Gracilaria algae is red macro algae which has demonstrated considerable antiinflammatory effects. Our objective was to compare the efficacy of Gracilaria algae topical cream 3% vs Clobetasol cream 0.05% in treatment of plaque-type psoriasis. Thirty adult patients with baseline modified Psoriasis Area and Severity Index (PASI) score ≤12 were randomized to receive either Clobetasol or Gracilaria algae cream on right or left-sided symmetric plaques once daily for 8 weeks and follow-up of 4 weeks. Modified PASI score, patient's satisfaction using VAS and global physician assessment score were assessed to evaluate clinical response. Thirty patients with 94 symmetrical psoriasis plaques were enrolled in this trial. The mean baseline modified PASI score of both sides was similar; however, at the end of trial, modified PASI score was reduced more on the sides treated with Gracilaria algae cream (0.80 ± 0.19% vs 0.63 ± 0.25%, P < .05). No significant difference was found regarding mean physician global assessment score between the two groups (P > .05). Patients' satisfaction was significantly higher in favor of algae cream only at week 8 of the intervention (P < .05). Gracilaria algae cream can be an effective and safe alternative of Clobetasol in the treatment of plaque type psoriasis.

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“…Prior to the studies above Hodak, et al[30] investigated the responds of activated immunologic cells and keratinocytes in psoriatic lesions to climatotherapy at the dead-sea for twenty-seven patients suffering from chronic, stable and plaque type psoriasis for twentyeight days using the quantitative histologic measures and the psoriasisCitation: Agan PN (2018) Climatotherapy the Need for Novel Applications in Nigeria . J Climatol Weather Forecasting 6: 223. doi: 10.4172/2332-2594.1000223…”

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confidence: 99%

Climatotherapy the Need for Novel Applications in Nigeria

Agan¹

2018

J Climatol Weather Forecasting

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Climatotherapy is the application of climatic elements for the treatments of skin diseases and infections which are vitiligo, atopic dermatitis, eczema etc. It also employs the utilization of springs, muds and clays of medicinal values through the inhalation, exposure and immersion for the treatment of chronic skin infections. Climatotherapy originated during the roman-empire and was a ritual practice amongst the Greeks, Babylonians and the Mesopotamians. It was founded by Hippocrates over 500 BC and has remain relevant since then even with the discovery and applications of pharmaceutical medicines. Climatotherapy also functions with other similar therapies which are balneotherapy, heliotherapy, fangotherapy, hydrotherapy, crenotherapy etc. The climate and geography of an area is the major determining factor in the application of spa therapy and climatotherapy and as such the most organized climatotherapy center is the Bulgaria coast of the black sea and the most widely visited and recognized climatotherapy center is the dead sea region in the middle east. Other areas of the world blessed with such sites for therapeutic use are the west Virginia springs, hot springs of Arkansas, Bedford's springs of Pennsylvania, Safaga area of Egypt amongst others. The Nigerian environments which include her sedimentary and basements terrains are replete with potentials for climatotherapy, balneotherapy, hydrotherapy etc. from the Ikogosi, Zuwan Zafi Numan and the Yankari springs to the Niger delta formation waters and the caves and fountains that dots the entire landscape of Nigeria. These are novel areas for the application of alternative medicine using rich natural medicinal waters and lakes. This research is a review to enunciate and elucidates on the full potentials of Nigeria as a promising climatotherapy and other forms of spa therapy hub in Africa. There is a need for the utilization of these sites for climatotherapy and their documentations. Nigeria has the potentials from these sites to compete with the great dead-sea region of the middle-east and others. This review also discovered areas for empirical research on climatotherapy and spa therapy in Nigeria through collaborations and synergy between medical practitioners, dermatologists, climatologist, geologist and other experts who are interested in exploring the natural environments for alternative and sustainable therapies.

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Dead sea climatotherapy for psoriasis vulgaris: analysis of short-term results

Cited by 6 publications

References 8 publications

Mind-Body Interventions as Alternative and Complementary Therapies for Psoriasis: A Systematic Review of the English Literature

Mind-Body Interventions as Alternative and Complementary Therapies for Psoriasis: A Systematic Review of the English Literature

Comparative evaluation of Gracilaria algae 3% cream vs Clobetasol 0.05% cream in treatment of plaque type psoriasis: A randomized, split‐body, triple‐blinded clinical trial

Climatotherapy the Need for Novel Applications in Nigeria

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