Dead Sea ultraviolet climatotherapy for children with atopic dermatitis

Kudish, A.I.; Marsakova, Anna; Jahn, Irmgard; Gkalpakiotis, Spyridon; Arenberger, Petr; Harari, Marco

doi:10.1111/phpp.12250

Cited by 7 publications

(3 citation statements)

References 21 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…In ever users, we stratified analyses according to specific categories of cumulative HCTZ use, in which the effect of dose–response was explored by estimating the incremental OR for each 10 000 mg of HCTZ using unconditional regression adjusted by age (continuous) and sex. The association was also examined stratifying by the following population subgroups: sex, age, never‐user of drugs with suggested photosensitizing properties, no diabetics, with low comorbidity (CCI = 0 in SIDIAP and none of the chronic diseases considered in BIFAP), with no history of actinic keratosis (associated with UV‐exposure and considered a precursor of KC 32 ), and no history of atopic dermatitis and psoriasis (associated to UV‐exposure and possibly associated with KC risk 33,34 ). Absolute risks with high use of HCTZ were estimated by IR*(IRR‐1) and they were used to calculate the number of patients needed to be exposed to cause one additional case per year.…”

Section: Methodsmentioning

confidence: 99%

Use of hydrochlorothiazide and risk of skin cancer in a large nested case‐control study in Spain

León‐Muñoz

Duarte‐Salles

Llorente

et al. 2021

Pharmacoepidemiology and Drug

View full text Add to dashboard Cite

Purpose Hydrochlorothiazide (HCTZ) use has been linked to skin cancer in northern European countries. We assessed the association between HCTZ exposure and risk of malignant melanoma (MM) and keratinocyte carcinoma (KC) in a European Mediterranean population. Methods Two parallel nested case‐control studies were conducted in Spain using two electronic primary healthcare databases, each one providing data on both exposure and outcomes: SIDIAP and BIFAP. Cancer cases were matched to 10 controls by age and gender through risk‐set sampling. The ORs and 95% CI for MM and KC associated with previous HCTZ use were estimated using conditional logistic regression. In BIFAP, KC cases were further identified as basal cell carcinoma (BCC) or squamous cell carcinoma (SCC). Results In adjusted analyses, both ever and cumulative high (≥50,000 mg) use of HCTZ were associated with an increased risk of KC. The risk estimates for high use were 1.30 (1.26–1.34) in SIDIAP and 1.20 (1.12–1.30) in BIFAP, with a lower risk for BCC (1.11 [1.02–1.21]) than for SCC (1.71 [1.45–2.02]). A dose–response relationship was observed between cumulative doses of HCTZ and KC risk. Inconsistent results were found for high use of HCTZ and risk of MM: 1.25 (1.09–1.43) in SIDIAP and 0.85 (0.64–1.13) in BIFAP. Conclusions In this European Mediterranean population, a high cumulative use of HCTZ was related to an increased risk of KC with a clear dose–response pattern.

show abstract

Section: Methodsmentioning

confidence: 99%

Use of hydrochlorothiazide and risk of skin cancer in a large nested case‐control study in Spain

León‐Muñoz

Duarte‐Salles

Llorente

et al. 2021

Pharmacoepidemiology and Drug

View full text Add to dashboard Cite

show abstract

“…Therefore, it is considered that 2-week HT is optimal as 3-week HT did not .0 units at T 2 and T 3 , respectively [27]. Additionally, the latter study was assessing climatotherapy on children with AD showing a persisting low SCORAD index with an overall average improvement of 71.3% 3 months after the therapy [28].…”

Section: Discussionmentioning

confidence: 99%

The long-term efficacy of heliotherapy in ameliorating disease severity and improving the quality of life in patients with atopic dermatitis

Terzić¹,

Mikić²,

Ljaljević³

et al. 2023

pdia

View full text Add to dashboard Cite

Introduction: Atopic dermatitis is one of the most common chronic inflammatory skin diseases adversely affecting the quality of life of both patients and their families. Heliotherapy, a treatment modality with high anti-inflammatory effects, is unjustifiably neglected in a country that has plenty of sunshine days throughout the year, but does not own the Cabinet for artificial phototherapy. Aim: To evaluate the power of individual heliotherapy in ameliorating disease severity and improving the quality of life, as well as to compare the results with those obtained from the studies evaluating group heliotherapies. Material and methods: We assessed disease severity and quality of life at three times: before commencing heliotherapy (Time 1), immediately after heliotherapy (Time 2), and 3 months after heliotherapy (Time 3). The tools we used are authorized scoring systems and questionnaires: SCORing Atopic Dermatitis (SCORAD), Eczema Area and Severity Index (EASI), Dermatology Life Quality Index (DLQI) and Severity of Pruritus Scale (SPS). Results: A total of 24 patients were analysed in this observational study. Good clinical results were observed with a statistically significant decrease in SCORAD index by 40% and 31.1% at Time 2 and Time 3, respectively (p < 0.001). Improvement in the quality of life was statistically significant showing a decrease in DLQI score by 31.57% 3 months after heliotherapy, comparing to baseline values (p < 0.001). Conclusions: Our results revealed that 2-week heliotherapy has shown satisfying, long-lasting effects in clearing the skin changes, reducing and ameliorating pruritus intensity, as well as improving the quality of life.

show abstract

“…During the First World War, sunlight therapy became known, and several hospitals and clinics were built with exposure to solar radiation in England and Germany [27,28]. Currently, sunbathing is used in the treatment of, among others: psoriasis [24,[29][30][31][32][33][34][35][36][37], atopic dermatitis [35,[38][39][40], acne vulgaris [38,41], as well as rickets, and other diseases associated with vitamin D deficiency [20,21,42,43]. In heliotherapy, the most important thing is the influence on the human body of the mid-ultraviolet light, whose biological activity is at a solar altitude >30 • [13,44].…”

Section: Introductionmentioning

confidence: 99%

Solar Climate Features Taking into Account the Morphometric Conditions of the Area and the Possibility of Using Them in Heliotherapy on the Example of the Cieplice and Kołobrzeg Health Resorts (Poland)

Szatten

Więcław

2021

Atmosphere

View full text Add to dashboard Cite

Global solar radiation is an important atmospheric stimulus affecting the human body and has been used in heliotherapy for years. In addition to environmental factors, the effectiveness of global solar radiation is increasingly influenced by human activity. This research was based on the use of heliographic and actinometric data (1996–2015) and the model distribution of global solar radiation to determine the possibility of heliotherapy with the example of two health resorts: Cieplice and Kołobrzeg (Poland). The solar features of health resorts (sunshine duration and global solar radiation) were characterized, and they were correlated with the spatial distribution of global solar radiation data obtained with the use of remote sensing techniques (System for Automated Geoscientific Analyzes-SAGA), including COoRdination and INformation on the Environment (CORINE) land cover (CLC) data. Using the maximum entropy model (MaxEnt), a qualitative and quantitative relationship between morphometric parameters and solar climate features was demonstrated for individual land cover types. Studies have shown that the period of late spring and summer, due to the climate’s solar features, is advisable for the use of heliotherapy. The human activity that determines the land cover is the main element influencing the spatial differentiation of the possibilities of using this form of health treatment. It also affects topographic indicators shown as significant in the MaxEnt predictive model. In general, areas with high openness were shown as predisposed for health treatment using global solar radiation, which is not consistent with areas commonly used for heliotherapy. The conducted research has shown the need for an interdisciplinary approach to the issue of heliotherapy, which will contribute to the optimization of the use of this form of health treatment from the perspective of climate change and human pressure.

show abstract

Dead Sea ultraviolet climatotherapy for children with atopic dermatitis

Abstract: Dead Sea climatotherapy represents a valuable option for the treatment of AD in children. Medically controlled and prescribed sun exposure seems to directly and positively influence the results obtained.

Cited by 7 publications

References 21 publications

Use of hydrochlorothiazide and risk of skin cancer in a large nested case‐control study in Spain

Use of hydrochlorothiazide and risk of skin cancer in a large nested case‐control study in Spain

The long-term efficacy of heliotherapy in ameliorating disease severity and improving the quality of life in patients with atopic dermatitis

Solar Climate Features Taking into Account the Morphometric Conditions of the Area and the Possibility of Using Them in Heliotherapy on the Example of the Cieplice and Kołobrzeg Health Resorts (Poland)

Contact Info

Product

Resources

About