* iMinds -SMIT (Vrije Universiteit Brussel) name.surname@vub.ac.be **iMinds -IBCN (Universiteit Gent) name.surname@intec.UGent.be Pervasive health systems aim to support society with the many challenges our healthcare system is facing today. Embedding systematically social choices in the Research and Development process (R&D) is therefore essential. In this chapter the 'Innovation Binder' approach is presented: a procedure to confront multiple viewpoints from user/social, technology and business perspective, to make choices (e.g. target groups, practices, actors, messages, means, steps, procedures, technologies) more explicit and coordinate the team to work together to a common abstract goal (e.g. home monitoring system to support ambient assistive living) with a lot of unknown viable options. The spine of our approach is the iterative use of scenarios and personas with different finalities and discussing them iteratively in team. It enables a parallel research track of social and technical R&D activities by coordinating mutual dependencies and uncertainties. We illustrate this approach with concrete examples from past and present R&D projects in the pervasive healthcare domain. This approach can help other R&D teams, convinced of the value of interdisciplinary work, to create desired pervasive health systems for multiple users.