Death and Relapse in Anorexia Nervosa: Survival Analysis of 151 Cases

Readiness for change and short‐term outcomes of female adolescents in residential treatment for anorexia nervosa

“…Other studies on AN have used survival analysis to examine events such as mortality, [67][68][69] relapse, 34,68,70 long-term recovery, 34,36 premature termination of treatment, 71 and symptom crossover. 72 In survival analysis, survival time is made up of two principal components: the follow-up time from a defined starting point and the occurrence of a defined event.…”

The long-term course of severe anorexia nervosa in adolescents: Survival analysis of recovery, relapse, and outcome predictors over 10-15 years in a prospective study

“…In this same regard, truly long-term observational studies of anorexia nervosa-for example, in excess of 10 yearsare less common, yet these, too, can give incomplete, if not seriously misleading, views of the illness. Apropos of this, long-term studies (Theander, 1992) shows that recovery may not be seen until 10 years or more following index assessment, whereas increasing lengths of observation also reveal continuing risk of death among those with intractable illness (Isager, Brinch, Kreiner, & Tolstrup, 1985;Theander, 1992). Longitudinal studies must also reckon with complex relationships among predictor variables, yet few studies to date have made use of multivariate statistical methods designed to isolate the independence of their effects.…”

“…To this end, our efforts have been informed directly by research on the long-term course of mood disorders (Keller, Shapiro, Lavori, & Wolfe, 1982a, 1982b. While several other groups have made effective use of survival analysis to characterize the course of anorexia nervosa (Isager et al, 1985;Herzog et al, 1993;Herzog, Schellberg, Deter, 1997), the present study is unique in two important respects: (a) the frequency of contacts with subjects over an extended course of their illness, and (b) the stringency of definitions of recovery and relapse based on these serial assessments. Thus, we have evaluated patients systematically at 6-month intervals through 5 years of follow-up, then annually until completion of the follow-up 10-15 years after their index admission.…”

A one-year follow-up study in anorexia nervosa. Dietary pattern and anthropometrical evolution

“…A relatively large number of studies has been carried out during refeeding and during in-hospital treatment, especially considering weight gain and changes in body composition of anorexia nervosa patients (Russell et al, 1983(Russell et al, , 1994Dempsey et al, 1984;Vaisman et al, 1988a,b;Melchior et al, 1989;Waller et al, 1996;Orphanidou et al, 1997). In addition, long term follow-up studies have been published measuring morbidity and mortality rates at time intervals between more than 4 y to 10 or 20 y since diagnosis (Theander, 1983;Isager et al, 1985;Steinhausen & Seidel, 1993;Eckert et al, 1995;Strober et al, 1997). These studies usually assess whether patients meet diagnostic criteria according to weight, eating behaviour and menstrual function and their psychiatric status and psychosocial adaptation.…”