Death caused by hydrogen peroxide

Zečević, Dušan; Gašparec, Z.

doi:10.1007/bf02091984

Cited by 13 publications

(2 citation statements)

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“…5 Ingestion of hydrogen peroxide may cause irritation of the gastrointestinal tract with nausea, vomiting, foaming at the mouth, multiple gastric ulcers and erosions in the duodenal bulb, haematemesis and gas embolism. [6][7][8] The foam may then obstruct the respiratory tract 9 or result in pulmonary aspiration. Ingestion of products with a concentration greater than 10% has been associated with a more severe outcome, 10 particularly in children.…”

Section: Discussionmentioning

confidence: 99%

Toxicity of traditional and soluble film automatic dishwashing tablets

Day

Sandilands

et al. 2019

Hum Exp Toxicol

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Introduction: Detergents used in automatic dishwashing machines are of two main types: traditional tablets that require removal from an external wrapper and newer soluble film tablets. Objective: To determine the toxicity of automatic dishwashing tablets. Methods: Telephone enquiries to the UK National Poisons Information Service were analysed for the period January 2008 to June 2019. Results: Ingestion: Ingestion was involved in 798 traditional tablet exposures and 725 soluble film exposures. Clinical features (Poisoning Severity Score ≥ 1) developed in 22.2% of patients ingesting traditional tablets and in 28.8% ingesting soluble film tablets; moderate or severe toxicity was rare (<0.5% for both traditional and soluble film tablets). Children (≤5 years) significantly ( p < 0.0001) more often developed features following ingestion of soluble film ( n = 193, 28.2%) than traditional tablets ( n = 134, 19.1%). In contrast, adults more often developed features following ingestion of traditional than soluble film tablets, although this difference was not statistically significant. Eye exposure: The eye was involved in only 26 of 1539 exposures; 17 of 26 exposures resulted in ocular features. The most commonly reported features were conjunctivitis, eye pain and blurred vision, although one patient sustained a corneal abrasion and developed loss of vision. Skin exposure: Thirty-four of 1539 exposures involved the skin but only 3 developed dermal features which were minor. Conclusions: Children (≤5 years) significantly more often developed features following ingestion of soluble film than traditional tablets, although the likelihood of a child developing features was relatively low (<30%) and features that did develop were almost always mild. In contrast, adults more often developed features following the ingestion of traditional than soluble film tablets. Overall, the eye was involved in only 1.7% of exposures and only one patient sustained a corneal abrasion.

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Section: Discussionmentioning

confidence: 99%

Toxicity of traditional and soluble film automatic dishwashing tablets

Day

Sandilands

et al. 2019

Hum Exp Toxicol

View full text Add to dashboard Cite

show abstract

“…[7] Ingestion of hydrogen peroxide may cause irritation of the gastrointestinal tract with nausea, vomiting, foaming at the mouth and hematemesis. [8] The foam may then obstruct the respiratory tract [9] or result in pulmonary aspiration. As the estimated maximal amount of hydrogen peroxide liberated from a typical dishwashing tablet (all the powder swallowed, completely dissolved and hydrogen peroxide fully released) is less than 1.3 g, it would not be anticipated that the more severe features reported after exposure to high strength hydrogen peroxide solutions would occur, unless several tablets were ingested deliberately.…”

Section: Discussionmentioning

confidence: 99%