Deaths in healthcare workers due to COVID‐19: the need for robust data and analysis

Kursumovic, Emira; Lennane, S.; Cook, Tim

doi:10.1111/anae.15116

Cited by 162 publications

(173 citation statements)

References 11 publications

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“…4,5 Whilst males are generally at higher risk of death from COVID-19 than females, 1 it is concerning that young female staff have been reported to have double the COVID-19 related mortality rate compared to age matched females in the general population. 1 It is possible that staff from minority ethnic groups, with higher mortality and morbidity risks from COVID-19, 6 are also at higher risk of failing fit tests due to different facial geometry. 1,7 Our study was limited by a lack of routinely recorded data on the sex of those undergoing fit testing.…”

mentioning

confidence: 99%

Respiratory personal protective equipment for healthcare workers: impact of sex differences on respirator fit test results

Ascott

Crowest

Sausmarez

et al. 2021

British Journal of Anaesthesia

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This is a PDF file of an article that has undergone enhancements after acceptance, such as the addition of a cover page and metadata, and formatting for readability, but it is not yet the definitive version of record. This version will undergo additional copyediting, typesetting and review before it is published in its final form, but we are providing this version to give early visibility of the article. Please note that, during the production process, errors may be discovered which could affect the content, and all legal disclaimers that apply to the journal pertain.

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mentioning

confidence: 99%

Respiratory personal protective equipment for healthcare workers: impact of sex differences on respirator fit test results

Ascott

Crowest

Sausmarez

et al. 2021

British Journal of Anaesthesia

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“…The impact may be more pronounced among Indo-Pacific communities as a result of high rates of non-communicable disease. 13 COVID-19 appears to be more severe in patients with diabetes, hypertension and chronic pulmonary illness, all of which are prevalent across the region. 13 Increasing demand is likely to expose pre-existing deficiencies in ED systems and resources, including scarce critical care capacity.…”

Section: Challenges For Emergency Departmentsmentioning

confidence: 99%

“…13 COVID-19 appears to be more severe in patients with diabetes, hypertension and chronic pulmonary illness, all of which are prevalent across the region. 13 Increasing demand is likely to expose pre-existing deficiencies in ED systems and resources, including scarce critical care capacity. 1,2 A survey of emergency care clinicians in the Pacific recently identified minimal integration of surge response with routine emergency care, and a lack of essential processes, such as triage and patient flow.…”

Section: Challenges For Emergency Departmentsmentioning

confidence: 99%

“…In the event of a surge, EDs will require significant increases in staffing, and the challenge may be exacerbated by high rates of comorbidities, absenteeism and inadequate training. 7,13 Additionally, many Indo-Pacific EDs rely on a sole medical leader for clinical and administrative decision making. 15 The pandemic may place these clinicians at risk of burnout, illness and death, thereby exacerbating the mismatch between supply and demand for care.…”

Section: Staffmentioning

confidence: 99%

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COVID‐19 and the Indo–Pacific: implications for resource‐limited emergency departments

Woodruff

Mitchell

Phillips

et al. 2020

Medical Journal of Australia

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“…Certain groups such as the elderly and those with particular comorbidities are more likely to die of COVID-19 ( 3 ). Healthcare workers in particular have experienced significant morbidity and mortality from COVID-19 ( 4 ), causing clear psychological impacts and threatening delivery of healthcare services ( 5 ). There is no known effective treatment for this virus and currently no available vaccine, with the result being that SARS-CoV-2 continues to spread throughout the virus naïve population of the world.…”

Section: Introductionmentioning

confidence: 99%

Progress and Pitfalls in the Quest for Effective SARS-CoV-2 (COVID-19) Vaccines

et al. 2020

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There are currently around 200 SARS-CoV-2 candidate vaccines in preclinical and clinical trials throughout the world. The various candidates employ a range of vaccine strategies including some novel approaches. Currently, the goal is to prove that they are safe and immunogenic in humans (phase 1/2 studies) with several now advancing into phase 2 and 3 trials to demonstrate efficacy and gather comprehensive data on safety. It is highly likely that many vaccines will be shown to stimulate antibody and T cell responses in healthy individuals and have an acceptable safety profile, but the key will be to confirm that they protect against COVID-19. There is much hope that SARS-CoV-2 vaccines will be rolled out to the entire world to contain the pandemic and avert its most damaging impacts. However, in all likelihood this will initially require a targeted approach toward key vulnerable groups. Collaborative efforts are underway to ensure manufacturing can occur at the unprecedented scale and speed required to immunize billions of people. Ensuring deployment also occurs equitably across the globe will be critical. Careful evaluation and ongoing surveillance for safety will be required to address theoretical concerns regarding immune enhancement seen in previous contexts. Herein, we review the current knowledge about the immune response to this novel virus as it pertains to the design of effective and safe SARS-CoV-2 vaccines and the range of novel and established approaches to vaccine development being taken. We provide details of some of the frontrunner vaccines and discuss potential issues including adverse effects, scale-up and delivery.

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Deaths in healthcare workers due to COVID‐19: the need for robust data and analysis

Cited by 162 publications

References 11 publications

Respiratory personal protective equipment for healthcare workers: impact of sex differences on respirator fit test results

Respiratory personal protective equipment for healthcare workers: impact of sex differences on respirator fit test results

COVID‐19 and the Indo–Pacific: implications for resource‐limited emergency departments

Progress and Pitfalls in the Quest for Effective SARS-CoV-2 (COVID-19) Vaccines

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