PurposeThe mounting health misinformation on social media triggers heated discussions about how to address it. Anchored by the influence of presumed influence (IPI) model, this study investigates the underlying process of intentions to combat health misinformation. Specifically, we analyzed how presumed exposure of others and presumed influence on others affect intentions to practice pre-emptive and reactive misinformation countering strategies.Design/methodology/approachCovariance-based structural equation modeling based on survey data from 690 Chinese participants was performed using the “lavaan” package in R to examine the proposed mechanism.FindingsPersonal attention to health information on social media is positively associated with presumed others’ attention to the same information, which, in turn, is related to an increased perception of health misinformation’s influence on others. The presumed influence is further positively tied to two pre-emptive countermeasures (i.e. support for media literacy interventions and institutional verification intention) and one reactive countermeasure (i.e. misinformation correction intention). However, the relationship between presumed influence and support for governmental restrictions, as another reactive countering method, is not significant.Originality/valueThis study supplements the misinformation countering literature by examining IPI’s tenability in explaining why individuals engage in combating misinformation. Both pre-emptive and reactive strategies were considered, enabling a panoramic view of the motivators of misinformation countering compared to previous studies. Our findings also inform the necessity of adopting a context-specific perspective and crafting other-oriented messages to motivate users’ initiative in implementing corrective actions.