Debittering of lemon juice using surface molecularly imprinted polymers and the utilization of limonin

Zhang, Jiawei; Tan, Ling; Zhang, Yuzhen; Zheng, Guolin; Xia, Zhining; Wang, Chong‐Zhi; Zhou, Ling; Zhang, Qi‐Hui; Yuan, Chun‐Su

doi:10.1016/j.jchromb.2018.11.025

Cited by 24 publications

(8 citation statements)

References 29 publications

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“…The limonin contents were determined according to the method described previously, with slight modification [40]. The supernatant of control and fermented lemon juice were harvested after centrifugation at 4000 r/min for 15 min.…”

Section: Determination Of Organic Acids and Limoninmentioning

confidence: 99%

Changes in Organic Acids, Phenolic Compounds, and Antioxidant Activities of Lemon Juice Fermented by Issatchenkia terricola

Liu,

Yuan,

et al. 2021

Molecules

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High content of citric acid in lemon juice leads to poor sensory experience. The study aimed to investigate the dynamics changes in organic acids, phenolic compounds, and antioxidant activities of lemon juice fermented with Issatchenkia terricola WJL-G4. The sensory evaluation of fermented lemon juice was conducted as well. Issatchenkia terricola WJL-G4 exhibited a potent capability of reducing the contents of citric acid (from 51.46 ± 0.11 g/L to 8.09 ± 0.05 g/L within 60 h fermentation) and increasing total phenolic level, flavonoid contents, and antioxidant activities compared to those of unfermented lemon juice. A total of 20 bioactive substances, including 10 phenolic acids and 10 flavonoid compounds, were detected both in fermented and unfermented lemon juice. The lemon juice fermented for 48 h had better sensory characteristics. Our findings demonstrated that lemon juice fermented with Issatchenkia terricola exhibited reduced citric acid contents, increased levels of health-promoting phenolic compounds, and enhanced antioxidant activities.

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Section: Determination Of Organic Acids and Limoninmentioning

confidence: 99%

Changes in Organic Acids, Phenolic Compounds, and Antioxidant Activities of Lemon Juice Fermented by Issatchenkia terricola

Liu,

Yuan,

et al. 2021

Molecules

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“…2 Lemon pulp contains fiber, vitamin C, vitamin B, flavonoids, limonin, trace elements, and other active ingredients. 3 Lemon can also reduce blood sugar, blood lipid levels, and blood pressure. Lemons are also effective in decreasing the harmful effects of cardiovascular diseases, some inflammation, tumors, and other malignant diseases.…”

Section: Introductionmentioning

confidence: 99%

“…However, a small part of the peel is used to make traditional Chinese medicine. 5 Lemon peel also has a variety of chemical compositions, such as abundant flavonoids, 3 which can be further developed and used for their health benefits.…”

Section: Introductionmentioning

confidence: 99%

Protective Effect of Lemon Peel Extract on Oxidative Stress in H9c2 Rat Heart Cell Injury

Wang¹,

Zhai²,

Ou³

et al. 2021

DDDT

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Aim: Lemon peel, a traditional Chinese medicine, was tested in this study for its novel application in inhibiting cellular oxidative stress, and the effect of lemon peel extract (LPE) on protecting H9c2 rat heart cells from oxidative stress was investigated. Methods: The scavenging effects of LPE on 1,1-diphenyl-2-picryhydrazyl (DPPH) and 2,2'azino-bis (3-ethylbenzthiazoline-6-sulfonic acid) (ABTS) free radicals were measured in extracellular experiments. The 3-(4,5-dimethyl-2-thiazolinyl)-2,5-diphenyl-2-h-tetrazolylammonium bromide (MTT) assay was used to detect the cell survival rate. The cell supernatant and intracellular oxidation-related indicators were detected by a kit, and the mRNA expression in H9c2 cells was detected by quantitative polymerase chain reaction (qPCR). The chemical substances of LPE were analyzed by high-performance liquid chromatography (HPLC). Results: The results showed that LPE exhibited better DPPH and ABTS free radical scavenging abilities than vitamin C. Compared with the cells in the normal state (control group), the cell survival rate in the model group decreased, and the level of lactate dehydrogenase (LDH) increased, the levels of superoxide dismutase (SOD), catalase (CAT), and glutathione (GSH) decreased, and the content of malondialdehyde (MDA) increased. Compared with the control group, the expression of Bcl-2-related X protein (Bax), caspase-3, nuclear factor erythroid 2-related factor 2 (Nrf2), and heme oxygenase-1 (HO-1) in the model group was increased, and the expression of B-cell lymphoma-2 (Bcl-2) was reduced. Compared with the model group, LPE treatment improved the cell survival rate, reduced the levels of LDH and MDA, increased the levels of SOD, CAT, and GSH, downregulated the expression of Bax, caspase-3, Nrf2 and HO-1, and upregulated the expression of Bcl-2. The composition analysis showed that LPE contained catechin, rutin, naringin, quercetin, and hesperidin. Conclusion:The results indicated that LPE could protect H9c2 cells from oxidative stress through five active components. LPE has the potential to be developed into natural medicine or health food for the inhibition of cell oxidative damage.

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“…The amount of adsorption of the material decreased with an excess zein, possibly because excess zein caused excessive polymerization and decreased the number of binding sites. 33 In this study, DESs were the functional monomer of the ZDM-MIPs. The amount of DESs was an essential parameter to the performance of ZDM-MIPs, which had been investigated to prepare the best ZDM-MIPs.…”

Section: Preparation Of Zdm-mipsmentioning

confidence: 99%

Specific adsorption and determination of aspartame in soft drinks with a zein magnetic molecularly imprinted modified MGCE sensor

Tan

et al. 2021

RSC Adv.

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Debittering of lemon juice using surface molecularly imprinted polymers and the utilization of limonin

Cited by 24 publications

References 29 publications

Changes in Organic Acids, Phenolic Compounds, and Antioxidant Activities of Lemon Juice Fermented by Issatchenkia terricola

Changes in Organic Acids, Phenolic Compounds, and Antioxidant Activities of Lemon Juice Fermented by Issatchenkia terricola

Protective Effect of Lemon Peel Extract on Oxidative Stress in H9c2 Rat Heart Cell Injury

Specific adsorption and determination of aspartame in soft drinks with a zein magnetic molecularly imprinted modified MGCE sensor

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