In this work, we present a recent study concerning the break-up of the Projectile-Like (PLF) into two fragments, following more violent deep-inelastic collisions in the reactions 78 Kr + 40 Ca and 86 Kr + 48 Ca at 10 A MeV, realized at INFN-Laboratori Nazionali del Sud by using the 4π multi detector CHIMERA. For these systems, we have already analyzed the fusion-evaporation and fission-like processes. A selection method has been developed, in order to discriminate PLF break up events from those due to other mechanisms which populate the same region of the phase-space. A preference for PLF aligned break-up, along the direction of the PLF-TLF separation axis with the light fragment emitted in the backward part, has been put in light, suggesting the presence of dynamical effects. Also a comparison between the neutron-rich 86 Kr + 48 Ca and neutron-poor 78 Kr + 40 Ca systems is presented, to put in evidence the isospin role in these processes.