With the growing population trends, the demand for electricity is accelerating rapidly. The policy planners and developers have great focus to utilize renewable energy resources (RERs) to encounter the scarcity of energy since they offer benefits to the environment and power systems. At present, the energy generation is evolving into a smart distribution system that assimilates several energy resources assuring to generate clean energy, to have reliable operational procedures, and to enhance the energy supervision and management arrangements. Therefore, the model of a distributed microgrid (DMG) with optimal energy management strategies based on multi-agent systems (MASs) technique has been focused in this chapter. Distributed energy resources (DER) have been considered for the generation of electrical power to fulfill the consumer's load demands. Thus, a fully controlled architecture of a grid along with concept of MAS and its development platforms, implementation, and operational procedures have been discussed in detail. In addition, agent's operations and their coordination within the MG arrangements have been focused by considering the supervision of the entire system autonomously. Moreover, optimal procedures of a microgrid (MG) energy supervision and power distribution system have also been presented considering the cost control and optimal operations of the entire MG at the distributed level.