Decentralized modular production to increase supply chain efficiency in chemical markets

Becker, Torsten; Bruns, Bastian; Lier, Stefan; Werners, Brigitte

doi:10.1007/s11573-020-01019-4

Cited by 14 publications

(13 citation statements)

References 23 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…The solvent is pumped to the production container to remove residues of previously Figure 1. Flow chart of the proposed process in small-scale production systems adopted from [3]. used substances in the equipment.…”

Section: Modular Production Systems For the Production Of Specialized Polymersmentioning

confidence: 99%

“…The optimization model determines the best production facility locations, the number and type of production modules at each facility, as well as all material and product flows from supplier to customer. For a more detailed discussion of the mathematical model, the interested reader is referred to [3,8,12].…”

Section: Scenario Descriptionmentioning

confidence: 99%

“…This short communication presents a case study to investigate the economic benefits of small-scale production systems for the production of specialized polymers. The paper is based on the previous results from Becker et al [3], with a stronger focus on chemical engineering. Real data provided by a large German chemical company is used to create a realistic scenario.…”

Section: Introductionmentioning

confidence: 99%

“…Real data provided by a large German chemical company is used to create a realistic scenario. A mathematical optimization model [3] is applied to prescribe an efficient production network structure with smallscale plants. Eight scenarios with different technological options and supply chain structures with respect to the production network costs are assessed.…”

Section: Introductionmentioning

confidence: 99%

“…Figure2. Survey of the locations of customers, potential production locations, and local suppliers adopted from[3].…”

mentioning

confidence: 99%

See 4 more Smart Citations

Efficient Production of Specialized Polymers with Highly Flexible Small‐Scale Plants

et al. 2021

Self Cite

View full text Add to dashboard Cite

Shortened product life cycles and increased demand for specialized products lead to more challenges in efficiently satisfying customer needs. Customer demands are increasingly uncertain in terms of type, location, and volume. As a result, more flexible chemical production plants are required. Modular small‐scale plants can be installed in transportation containers and, therefore, offer the flexibility of easy relocation, enabling production close to the customer or supplier. In a mathematical optimization model, the economic benefit of small‐scale plants in the specialty chemicals market of polymer production is analyzed. Different scenarios created from the real data of a chemical company show that the use of small‐scale plants may lead to a significant reduction in total costs that is mainly due to the transportation costs of raw materials and products.

show abstract

Section: Modular Production Systems For the Production Of Specialized Polymersmentioning

confidence: 99%

Section: Scenario Descriptionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

“…Figure2. Survey of the locations of customers, potential production locations, and local suppliers adopted from[3].…”

mentioning

confidence: 99%

See 3 more Smart Citations

Efficient Production of Specialized Polymers with Highly Flexible Small‐Scale Plants

et al. 2021

Self Cite

View full text Add to dashboard Cite

show abstract

Multistage stochastic programming for the closed‐loop supply chain planning with mobile modules under uncertainty

Zhang

et al. 2023

AIChE Journal

View full text Add to dashboard Cite

Traditional supply chains usually follow fixed facility designs which coincide with the strategic nature of supply chain management (SCM). However, as the global market turns more volatile, the concept of mobile modularization has been adopted by increasingly more industrial practitioners. In mobile modular networks, modular units can be installed or removed at a particular site to expand or reduce the capacity of a facility, or relocated to other sites to tackle market volatility. In this work, we formulate a mixed‐integer linear programming (MILP) model for the closed‐loop supply chain network planning with modular distribution and collection facilities. To further deal with uncertain customer demands and recovery rates, we extend our model to a multistage stochastic programming model and efficiently solve it using a tailored stochastic dynamic dual integer programming (SDDiP) with Magnanti‐Wong enhanced cuts. Computational experiments show that the added Magnanti‐Wong cuts in the proposed algorithm can effectively close the gap between upper and lower bounds, and the benefit of mobile modules is evident when the temporal and spatial variability of customer demand is high.

show abstract

Exploration and evaluation of modular concepts for the design of full‐scale pharmaceutical manufacturing facilities

Bertran,

Babi

2023

Biotech & Bioengineering

View full text Add to dashboard Cite

The design of biopharmaceutical processes is predominantly driven by the domain of experimental process design. This approach can be further improved by combining multiple domain information such as experiments, unit models, and flowsheet models. Approaches consisting of methods and flowsheet models provide the framework for exploring, analyzing, and ultimately evaluating the combinatorial space of all possible designs within the molecule‐to‐manufacturing value chain. In recent years, modular process designs are of interest in the pharmaceutical industry because of the shift toward multiproduct, mutiprocess processes. Therefore, a systematic approach for how to evaluate the utilization of the modular plug‐n‐play concept provides metrics that can propel modular design from a viable design alternative to the selected alternative for full‐scale manufacturing. The objective of this paper is to present such an in silico approach for the evaluation of modular designs. The approach is presented as a systematic method and then, is exemplified through the manufacture of an active pharmaceutical ingredient (API). The application of the method shows how to transition from a typical design‐for‐purpose design alternative to a modular design through the utilization of data, modeling, simulation, and uncertainty/sensitivity analyses for quantification of various selection metrics such as process robustness and flexibility.

show abstract

Decentralized modular production to increase supply chain efficiency in chemical markets

Cited by 14 publications

References 23 publications

Efficient Production of Specialized Polymers with Highly Flexible Small‐Scale Plants

Efficient Production of Specialized Polymers with Highly Flexible Small‐Scale Plants

Multistage stochastic programming for the closed‐loop supply chain planning with mobile modules under uncertainty

Exploration and evaluation of modular concepts for the design of full‐scale pharmaceutical manufacturing facilities

Contact Info

Product

Resources

About