The current study sought to assess the dyadic effects of affection deprivation in marital relationships. We used the tenets of affection exchange theory to examine the actor and partner effects between affectionate communication, affection deprivation, and mental and relational outcomes. Moreover, we tested whether affection deprivation mediated the association between affectionate communication and outcome variables. In terms of actor effects, affectionate communication was associated with husbands’ depression, wives’ loneliness, and both husbands’ and wives’ marital quality and emotional intimacy. Affection deprivation was associated with all outcome variables for husbands and wives, except for wives’ emotional intimacy. We observed significant partner effects between affectionate communication and affection deprivation for both husbands and wives, as well as between wives’ affectionate communication and husbands’ emotional intimacy. Affection deprivation mediated some of the actor and partner effects between affectionate communication and outcome variables. Implications, connections to theory, and directions for future research are discussed.