2024
DOI: 10.3389/fimmu.2023.1332943
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Deciphering decidual leukocyte traffic with serial intravascular staining

Jessica Vazquez,
Mona A. Mohamed,
Soma Banerjee
et al.

Abstract: The decidual immunome is dynamic, dramatically changing its composition across gestation. Early pregnancy is dominated by decidual NK cells, with a shift towards T cells later in pregnancy. However, the degree, timing, and subset-specific nature of leukocyte traffic between the decidua and systemic circulation during gestation remains poorly understood. Herein, we employed intravascular staining in pregnant C57BL/6J mice and cynomolgus macaques (Macaca fascicularis) to examine leukocyte traffic into the decidu… Show more

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