2015
DOI: 10.3389/fped.2015.00061
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Decision-making for surgery in the management of patients with univentricular heart

Abstract: A series of technical refinements over the past 30 years, in combination with advances in perioperative management, have resulted in dramatic improvements in the survival of patients with univentricular heart. While the goal of single-ventricle palliation remains unchanged – normalization of the pressure and volume loads on the systemic ventricle, the strategies to achieve that goal have become more diverse. Optimal palliation relies on a thorough understanding of the changing physiology over the first years o… Show more

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Cited by 29 publications
(25 citation statements)
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References 219 publications
(301 reference statements)
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“…With a follow-up of almost 6 years, and only 13% lost to follow-up, the level of follow-up of children supported by Mécénat-Chirurgie Cardiaque is in line with that of the French university hospitals and international studies 2 and demonstrates the effectiveness of the networks put in place between Mécénat-Chirurgie Cardiaque and the referents of the countries sending their children to us, despite the geographical distance and the difficulties encountered locally. The care of these children who sometimes require two or three interventions 3 should not be hampered by the fear of insufficient follow-up due to remoteness. Nevertheless, in the children who underwent a total cavo-pulmonary connection, the delay between the first medical intervention in France and the completion of the cavo-pulmonary connection was long (almost 8 years), when the current strategy suggests a delay of 2 years until completion.…”
Section: Discussionmentioning
confidence: 99%
“…With a follow-up of almost 6 years, and only 13% lost to follow-up, the level of follow-up of children supported by Mécénat-Chirurgie Cardiaque is in line with that of the French university hospitals and international studies 2 and demonstrates the effectiveness of the networks put in place between Mécénat-Chirurgie Cardiaque and the referents of the countries sending their children to us, despite the geographical distance and the difficulties encountered locally. The care of these children who sometimes require two or three interventions 3 should not be hampered by the fear of insufficient follow-up due to remoteness. Nevertheless, in the children who underwent a total cavo-pulmonary connection, the delay between the first medical intervention in France and the completion of the cavo-pulmonary connection was long (almost 8 years), when the current strategy suggests a delay of 2 years until completion.…”
Section: Discussionmentioning
confidence: 99%
“…80 In addition, augmented PBF may decrease the stimulus for the development or actual regression of PAVMs and systemic-to-pulmonary collateralization. 81 This approach is not without disadvantages. Adding additional sources of PBF imposes a persistent volume load on the remodeling ventricle, which may worsen AVVR or ventricular function, particularly in single ventricle patients where the additional blood source is an aortopulmonary shunt.…”
Section: Surgical Methods Of Augmenting Pulmonary Blood Flowmentioning
confidence: 99%
“…Neonates present a particular challenge as their pulmonary vascular resistance is elevated early in life, requiring a staged approach to control pulmonary blood flow and allow development of the vascular bed (7). Furthermore, infants with low birth weight, prematurity, and coexisting comorbidities add increased complexity and challenges.…”
Section: Hybrid Stage I Palliation In Hlhsmentioning
confidence: 99%