Objective: While there is increasing research on effects of acute stress on moral decision-making, evidence regarding underlying neural mechanisms is scarce. Thus, the aim of the present study was to increase knowledge on neural correlates of everyday moral decision-making after exposure to two versions of the neuroimaging stress protocol ScanSTRESS. Method: We confronted half of the total sample (N = 40 males) to the original ScanSTRESS paradigm with pronounced psychosocial stress components (ScanSTRESS PS+) and half to a modified version without these components (ScanSTRESS PS−). Subsequently, participants performed an everyday moral decision-making task. Results: Regarding cortisol, heart rate, and affect, ScanSTRESS exposure led to typical changes over time, but there was an absence of group differences between the two ScanSTRESS versions. However, more activations in (pre)limbic structures were found during ScanSTRESS PS+ compared to PS−. Depending on the presence of psychosocial stress components, cortisol increases were differently associated with striatolimbic responses. Concerning everyday moral decision-making, we observed neither behavioral between-group differences nor associations with cortisol. On a neural level, whole-brain analyses (total sample) revealed higher responses in a broad cluster comprising frontotemporal and cingulate regions when everyday moral versus neutral social conflicts were contrasted. Compared to the PS− group, higher responses in the precuneus and middle cingulate cortex were detected in the PS+ group when altruistic versus egoistic decisions were made. Conclusions: First, we found preliminary evidence suggesting (striato)limbic structures respond differently to the presence or absence of psychosocial stress components. Second, we could extend knowledge on neural correlates of everyday moral decision-making after exposure to two versions of the ScanSTRESS paradigm, although the establishment of a nonstress control condition is still pending and would be desirable for future studies.