The polymer science at Zhejiang University (ZJU) is well known for its foremost origin of study and education of polymers in China. According to the latest US News rankings, it is ranked third in the subject of Polymer Sciences. The Department of Polymer Science and Engineering (DPSE) is one of the earliest academic institutions devoted to polymers at ZJU. Under the leadership of Prof. Zhi-Quan Shen and Prof. Jia-Chong Shen, academicians of the Academia Sinica, 54 faculty members (including 28 professors, 26 associate professors, and senior researchers) are now working in education and scientific research of polymer sciences, polymer composites and biomedical macromolecules. Our faculty is among the finest all over the nation, leading polymer science and engineering research. Our department has been developed as a collaborative community of faculties, students, and alumni dedicated to research developments and solving important technical questions with three decades of endeavors.In this special issue of ZJU, we aim to share a selection of recent research activities from our faculties, students, and alumni, classified into the following six topics: controlled polymerization, polymer physics and rheology, biomedical polymers, polymer membranes and films, organic and polymeric photo-electronic functional materials, and aggregationinduced emission (AIE) and graphene materials.The topic of controlled polymerization illustrates the fabrication of fine polymers with sophisticated polymerization techniques. A protocol of using readily available raw materials of ethylene oxide, propylene oxide, and carbonyl sulfide is developed by Zhang et al. to synthesize sulfur-rich poly(thioether)s that exhibit T m values ranging from 76 C to 144 C and have high refractive index up to 1.68. Du et al. synthesize a series of ABCBA symmetrical amphiphilic pentablock terpolymers with various block lengths two-step atom transfer radical polymerization. These polymers can form high-genus vesicles in dilute aqueous solutions. In another study, Ling et al. design the synthesis of P(EVL-alt-EDT)-g-PEG combining thiol-ene click polymerization and ring-opening grafting reaction. The obtained polymers consist of a hydrophobic backbone of alternative copolymers of disubstituted