Abstract-Construction of university Data Center is the requirement of higher education to adapt to information society, is also an important part of the construction of universities. At present, due to the informationization construction of universities lacking of unified planning and deployment, as well as the research and application of the Data Center is not enough in-depth, the needs of current management and service works could not be meet that result in delaying the informationization development. Taking the construction of Cloud Data Center to realize wisdom campus as the goal, this paper puts forward a set of construction plan of Data Center based on Cloud Computing that suitable for the application characteristics of universities, and implemented the plan in the Cloud Data Center project in Lanzhou Jiaotong University. Implementation of Cloud Data Center project in university could create a reliable platform for construction, circulation and sharing of information resources, and have obvious advantages in promoting ability of informationization integration application, management efficiency of information system, and quality of Data Center operation and reducing operation cost.