Decline in Cervical Cancer Incidence and Mortality in New South Wales in Relation to Control Activities (Australia)

Taylor, Richard; Morrell, Stephen; Mamoon, Hassan; Wain, Gerard; Ross, Jayne

doi:10.1007/s10552-005-0515-z

Cited by 30 publications

(25 citation statements)

References 21 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Several studies demonstrated that cervical canser screening by Pap test reduces mortality rates. (Nygard et al, 2002;Abed et al, 2006;Aklimunnessa et al, 2006;Taylor et al, 2006). Currently, there is no organized population-based screening program available for the whole World.…”

Section: Discussionmentioning

confidence: 99%

Population-Based Cervical Screening Outcomes in Turkey over a Period of Approximately Nine and a Half Years with Emphasis on Results for Women Aged 30-34

Şengül¹,

Altınay²,

Oksuz³

et al. 2014

Asian Pacific Journal of Cancer Prevention

View full text Add to dashboard Cite

Section: Discussionmentioning

confidence: 99%

Population-Based Cervical Screening Outcomes in Turkey over a Period of Approximately Nine and a Half Years with Emphasis on Results for Women Aged 30-34

Şengül¹,

Altınay²,

Oksuz³

et al. 2014

Asian Pacific Journal of Cancer Prevention

View full text Add to dashboard Cite

“…3 This programme has been highly successful in reducing cervical cancer incidence and mortality in Australia, 3,4 including in New South Wales (NSW), the most populous Australian state. 5 The current recommended cervical screening policy in Australia is routine screening with Pap smears every two years for women who have ever been sexually active and have no symptoms or history suggestive of cervical pathology. 4,6 During the five year period (1 July Integral to the NSW Cervical Screening Program is the opt-off Pap Test Register (PTR) which (1) records all Pap tests and cervical histology tests and their results on NSW women; (2) acts as a safety net for screening reminders for women who are overdue for a subsequent test; and (3) is charged with implementing a programme of quality assurance at all steps along the screening pathway.…”

Section: Introductionmentioning

confidence: 99%

High-grade cervical abnormalities and screening intervals in New South Wales, Australia

et al. 2008

Self Cite

View full text Add to dashboard Cite

Objectives This study aims to determine the association of two versus three year screening intervals with the likelihood of detection of a high-grade cervical abnormality and cervical cancer. Methods Data were obtained from the New South Wales (NSW) Papanicolaou (Pap) Test Register (PTR) and NSW Central Cancer Registry (CCR). Subjects were human papillomavirus (HPV) unvaccinated women aged 20-69 years who had a minimum of two Pap tests with a negative result at their first recorded Pap test (n ¼ 1,213,295). Logistic regression was used to determine the association between screening interval and the likelihood of: (1) a cytological prediction of high-grade abnormality, defined as cervical intraepithelial neoplasia (CIN) 2 or greater; (2) a histologically confirmed high-grade abnormality; (3) a cytological prediction of cervical cancer and (4) a confirmed diagnosis of cervical cancer, controlling for potential confounders of age and socioeconomic status (SES) of area of residence.Results For each year increase in the screening interval, the odds of a histologically confirmed highgrade abnormality increased significantly in women aged 20 -29 years (odds ratio [OR] 1.24, 95% confidence interval [CI] 1.20-1.28) and in women aged 30 -49 years (OR 1.11, 95% CI 1.06 -1.16), but not in women aged 50 -69 years (OR 1.08, 95% CI 0.89 -1.32). Similar results were observed for cytologically detected high-grade abnormalities. The screening interval was significantly and positively associated with a cytological prediction of cervical cancer (OR 1.40, 95% CI 1.28 -1.54) and a confirmed cervical cancer diagnosis (OR 1.66, 95% CI 1.33 -2.07) in women aged 20 -69 years. We estimate that if the screening interval were increased from two to three years, and the number of women participating in triennial screening participation was the same as for biennial participation in NSW, then 267 (95% CI 186-347) extra cases of highgrade abnormalities would be detected annually by cytology and 225 extra cases (95% CI 160-291) confirmed by histology, mostly confined to women aged 20 -49 years. Equivalently, 2.3 (95% CI 1.8 -2.8) and 1.9 (95% CI 1.5-2.4) extra cases of high-grade cytology and histology, respectively, would be expected per 1000 women with initially negative cytology if the screening interval were extended from two to three years. Conclusion Increasing the cervical screening interval from two to three years would be expected to significantly increase the odds of detection of a high-grade abnormality for NSW women aged 20 -49 years and cervical cancer for NSW women aged 20 -69 years. Accordingly, our study provides evidence in support of retaining the recommended cervical screening interval at two years for HPV unvaccinated, well women.

show abstract

“…To exemplify, from a brief literature search we suspect that the results of Yu et al, 2006 may be significantly affected by the artefactual degree-of-spread data 5 and other publications perhaps less so. 3,12 Accordingly, we strongly recommend that researchers who may have used degree-of-spread information provided by the NSW CCR in the past review carefully the implications of this report in relation to any results that they may have reported, or with regard to any policies that may have emanated from such results.…”

Section: Discussionmentioning

confidence: 99%

“…Two major uses of the degree-of-spread data are to evaluate the effectiveness of screening programs [1][2][3] and to analyse the survival of patients by extent of disease at first presentation. 4,5 Degree-of-spread represents the most aggressive extent of the disease based on diagnostic and therapeutic evidence.…”

mentioning

confidence: 99%

Degree‐of‐spread artefact in the New South Wales Central Cancer Registry

Barraclough

Morrell

Arcorace

et al. 2008

Australian and New Zealand Journal of Public Health

Self Cite

View full text Add to dashboard Cite

Decline in Cervical Cancer Incidence and Mortality in New South Wales in Relation to Control Activities (Australia)

Cited by 30 publications

References 21 publications

Population-Based Cervical Screening Outcomes in Turkey over a Period of Approximately Nine and a Half Years with Emphasis on Results for Women Aged 30-34

Population-Based Cervical Screening Outcomes in Turkey over a Period of Approximately Nine and a Half Years with Emphasis on Results for Women Aged 30-34

High-grade cervical abnormalities and screening intervals in New South Wales, Australia

Degree‐of‐spread artefact in the New South Wales Central Cancer Registry

Contact Info

Product

Resources

About