2022
DOI: 10.1002/jmv.28010
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Decline in human T‐cell lymphotropic virus seroprevalence in blood donors from Minas Gerais, Brazil over a 12‐year period (2006–2017)

Abstract: To investigate a 12-year historical series (2006)(2007)(2008)(2009)(2010)(2011)(2012)(2013)(2014)(2015)(2016)(2017) of human T-cell lymphotropic virus (HTLV)-positive blood donations from Fundação Hemominas, Minas Gerais, Brazil, an observational retrospective study was performed to evaluate data of blood donor candidates who were screened for HTLV-1/2 by enzyme-linked immunosorbent assay or chemiluminescence assays and confirmed by Western blot. We analyzed 3 309 716 blood donations covering 2006-2017 that we… Show more

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“…Therefore, the adoption of a more specific test was an important gain for the institution. On the other hand, it is important to highlight that the decrease in reactivity to HTLV may not only be due to changing the screening kit but also may be due to a previously observed trend of decreasing seroprevalence for HTLV in the HEMOMINAS blood donor population [18], as well as to a change in the donor profile by the increase in the repeat donor rate during the COVID-19 pandemic [19].…”
Section: Discussionmentioning
confidence: 99%
“…Therefore, the adoption of a more specific test was an important gain for the institution. On the other hand, it is important to highlight that the decrease in reactivity to HTLV may not only be due to changing the screening kit but also may be due to a previously observed trend of decreasing seroprevalence for HTLV in the HEMOMINAS blood donor population [18], as well as to a change in the donor profile by the increase in the repeat donor rate during the COVID-19 pandemic [19].…”
Section: Discussionmentioning
confidence: 99%