2007
DOI: 10.1016/s0140-6736(07)60564-9
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Decline in pneumonia admissions after routine childhood immunisation with pneumococcal conjugate vaccine in the USA: a time-series analysis

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Cited by 601 publications
(446 citation statements)
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“…, 12 , 14 In this study, the average coverage rate in the year that the vaccine was introduced was only 52.7%; however, in 2011, 2012, and 2013 the rates were 104.0%, 102.9%, and 103.1%, respectively, which is above the recommended. It is expected, therefore, a reduction in the number of CAP cases and its consequences, such as hospitalization and mortality, which was actually seen.…”
Section: Discussioncontrasting
confidence: 51%
“…, 12 , 14 In this study, the average coverage rate in the year that the vaccine was introduced was only 52.7%; however, in 2011, 2012, and 2013 the rates were 104.0%, 102.9%, and 103.1%, respectively, which is above the recommended. It is expected, therefore, a reduction in the number of CAP cases and its consequences, such as hospitalization and mortality, which was actually seen.…”
Section: Discussioncontrasting
confidence: 51%
“…9,17 Grijalva's study in the US found a higher national annual pneumococcal pneumonia hospitalization rates among adults (18 years and more) than observed in this study, even when correction to include private sector was considered. 9 Differences in the access to secondary care in hospital settings, in care practices, health information systems, and true variations in population PD incidence and lethality rates may account for the differences in hospitalization rates between the two countries.…”
Section: Discussionmentioning
confidence: 99%
“…En varios países la implementación y el uso de vacunas conjugadas neumocóccicas (VCN), ha determinado un impacto muy importante en la epidemiología de las infecciones graves por S. pneumoniae, disminuyendo drásticamente las tasas de las mismas, fundamentalmente en niños bajo dos años de edad 5,[8][9][10][11][12][13][14] . Estas vacunas también han demostrado tener un efecto de inmunidad de rebaño muy importante, reduciendo la incidencia de enfermedad neumocóccica invasora (ENI) en poblaciones que no la recibieron, como los niños sobre 5 años y adultos de todas las edades 5,9,10,[15][16][17][18] .…”
Section: Introductionunclassified
“…Estas vacunas también han demostrado tener un efecto de inmunidad de rebaño muy importante, reduciendo la incidencia de enfermedad neumocóccica invasora (ENI) en poblaciones que no la recibieron, como los niños sobre 5 años y adultos de todas las edades 5,9,10,[15][16][17][18] . Por cada niño vacunado, 2,2 personas no vacunadas se benefician por el efecto rebaño, atribuible, en parte, a la disminución en la colonización oro-faringea en los vacunados 14 . Para obtener este efecto, la vacunación debe ser universal, con una cobertura de al menos 80 a 90% de la población objetivo.…”
Section: Introductionunclassified