Declining prevalence of allergic contact dermatitis caused by toslyamide/formaldehyde in nail polish

Lee, Senhong; Maor, Danit; Palmer, Amanda; Nixon, Rosemary

doi:10.1111/cod.13020

Cited by 12 publications

(5 citation statements)

References 11 publications

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“…It can cause skin irritation and allergic reactions, and long-term exposure may pose health risks. There has been a decline in sensitization to tosylamide/formaldehyde resin, a common ingredient found in "classical" nail polish, while the incidence of (meth)acrylate-related allergic contact dermatitis (ACD) has been on the rise [16].…”

Section: Associated Allergensmentioning

confidence: 99%

Emerging Trends in Gel Nail Allergies: Prevalence, Symptoms, and Occupational Hazards Associated with Acrylate Sensitization

Zembala,

Zembala

et al. 2023

J Educ Health Sport

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Introduction and objective Gel nail allergies have become a growing concern in recent years, as individuals experience adverse immune reactions to the chemicals present in gel nail products. The popularity of gel nails, known for their long-lasting and durable finish compared to traditional nail polishes, has increased in the beauty industry. However, specific constituents, particularly acrylate compounds used in gel nail formulations, can trigger allergic responses in susceptible individuals. Abbreviated description of the state of knowledge Findings from the reviewed articles indicate that allergic reactions to acrylates in gel nail products can manifest in various ways, including contact dermatitis, dermatoses, and general allergic responses. Nail technicians, due to their frequent exposure to gel nail products and other potential allergens, are particularly vulnerable to occupational hazards associated with acrylate sensitization. These insights highlight the need for preventive measures to protect the health and well-being of nail technicians and promote a safer working environment. Summary This literature review addresses the emerging issue of gel nail allergies and provides valuable information regarding the prevalence and characteristics of allergic reactions to acrylates. The article underscores the significance of increasing awareness, implementing preventive measures, and effectively managing gel nail allergies. By doing so, the beauty industry can ensure a safer approach to gel nail applications, benefitting both nail technicians and consumers alike.

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Section: Associated Allergensmentioning

confidence: 99%

Emerging Trends in Gel Nail Allergies: Prevalence, Symptoms, and Occupational Hazards Associated with Acrylate Sensitization

Zembala,

Zembala

et al. 2023

J Educ Health Sport

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“…Neben Nageldesignern in zahlreichen Nagelstudios [156-158] bietet die Heimanwendung von Kits für künstliche Nägel oder für „lang anhaltenden Nagellack“ weitere Möglichkeiten der Sensibilisierung [159]. Der steigende Trend der (Meth)acrylat-bedingten ACD spiegelt sich in einem Abwärtstrend der Sensibilisierung auf Tosylamid/Formaldehyd-Harz, einem Bestandteil von „klassischem“ Nagellack, wider [160]. Die Quellen der Exposition und somit der Sensibilisierung und/oder Auslösung von ACD gegen (Meth)acrylate können bisweilen unerwartet sein.…”

Section: Ergebnisseunclassified

Kontaktallergien – Neu aufkommende Allergene und Auswirkungen für das Gesundheitswesen

Uter¹,

Werfel

Lepoittevin

et al. 2021

Kompass Dermatol

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Kontaktallergie (Sensibilisierung) und daraus resultierende allergische Kontaktdermatitis (ACD) sind von erheblicher Tragweite aus Sicht des Gesundheitswesens. Für die vorliegende Übersichtsarbeit hierzu wurden alle passenden Artikel aus dem Zeitraum 2018–2019 per systematischer Suche in Medline und Web of Science<sup>TM</sup> ermittelt; außerdem wurden alle verfügbaren Ausgaben der Fachzeitschriften „Contact Dermatitis“ und „Dermatitis“ manuell durchsucht und so eine frühere, ähnliche Übersichtsarbeit fortgeschrieben und neu fokussiert. Neue Allergene ebenso wie bekannte Allergene, die in neuem Expositionskontext gefunden wurden oder deren Bedeutung in sonstiger Hinsicht neu bewertet wurde, werden in Abschnitten nach Substanzklasse gegliedert beschrieben (z. B. Metalle, Konservierungsmittel, Duftstoffe). Als gemeinsames Ergebnis zahlreicher Untersuchungen fällt sowohl ein Mangel an Informationen über die Produktzusammensetzung auf, z. B. in Bezug auf ein neu beschriebenes Allergen in Leinenturnschuhen (Dimethylthiocarbamylbenzothiazolsulfid), als auch vor allem die mangelnde Kooperativität von Herstellern von Blutzuckermessgeräten bzw. Insulinpumpen. Zu den letztgenannten Geräten hat eine internationale Zusammenarbeit zwischen Dermatologen und Chemikern gezeigt, dass sie bei zahlreichen Diabetikern schwere ACD verursachen, indem sie Isobornylacrylat bzw. N,N’-Dimethylacrylamid freisetzen. Eine verbesserte und vollständige Deklaration der Inhaltsstoffe für Produkte alle Art – und nicht nur, wie wir es derzeit in Europa haben, bei Kosmetika (abgesehen von der vollständigen Auflistung der Duftstoffe) – muss auf die legislative Agenda gesetzt werden.

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“…Besides nail technicians in the numerous nail salons [156][157][158], home use of kits either for artificial nails or "long-lasting nail polish" offer other opportunities for sensitisation [159]. The upward trend regarding (meth)acrylate-related ACD is mirrored by a downward trend of sensitisation to tosylamide/formaldehyde resin, a constituent of "classical" nail polish [160]. Sources of exposure and, thereby, sensitisation and/or elicitation of ACD to (meth)acrylates may sometimes be unexpected.…”

Section: Plastic Monomers and Rubbermentioning

confidence: 99%

Contact Allergy—Emerging Allergens and Public Health Impact

Uter

Werfel

Lepoittevin

et al. 2020

IJERPH

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Contact allergy (sensitisation) and allergic contact dermatitis (ACD) resulting from it have a considerable public health impact. For the present review, all pertinent articles were systematically searched via Medline and Web of Science™; additionally, all available issues of the journals “Contact Dermatitis” and “Dermatitis” were manually searched, covering the years 2018–2019, thereby extending and re-focusing a previous similar review. New allergens, or previously described allergens found in a new exposure context or of other current importance, are described in sections according to substance classes, e.g., metals, preservatives, fragrances. As a common finding in many investigations, a lack of information on product composition has been noted, for instance, regarding a newly described allergen in canvas shoes (dimethylthiocarbamylbenzothiazole sulfide) and, most notably, absence of co-operation from manufacturers of glucose-monitoring devices and insulin pumps, respectively. These latter devices have been shown to cause severe ACD in a considerable number of diabetic patients caused by the liberation of isobornyl acrylate and N,N’-dimethylacrylamide, respectively, as demonstrated by an international collaboration between dermatologists and chemists. Improved and complete ingredient labelling for all types of products, and not just as we have with cosmetics at present (apart from full listing of fragrance substances) in Europe, must be put on the legislative agenda.

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Declining prevalence of allergic contact dermatitis caused by toslyamide/formaldehyde in nail polish

Cited by 12 publications

References 11 publications

Emerging Trends in Gel Nail Allergies: Prevalence, Symptoms, and Occupational Hazards Associated with Acrylate Sensitization

Emerging Trends in Gel Nail Allergies: Prevalence, Symptoms, and Occupational Hazards Associated with Acrylate Sensitization

Kontaktallergien – Neu aufkommende Allergene und Auswirkungen für das Gesundheitswesen

Contact Allergy—Emerging Allergens and Public Health Impact

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