Declining Prevalence of Helicobacter Pylori Infection- A 13C Urea Breath Test (UBT) Based Study in Symptomatic

Abstract

Background: Helicobacter pylori (HP) infection is an important cause of peptic ulcer disease (PUD) in the world. This study was aimed to know the trend of H.P. infection among the symptomatic subjects
 Method: This was a retrospective observational study conducted from January 2015 to July 2018 in three different hospitals in Dhaka city. Patient who presented with dyspepsia underwent 13C urea breath test. Positive cases were analyzed. Results: A total 1343 patients were taken for UBT where 308 (23%) patients were found positive. The mean age group was 41.21+13.6. Male were more infected (61%) than female (39%).
 Conclusion: Improving sanitary and hygienic condition of this region along with significantly increasing HP eradication therapy and PPI use by the symptomatic individuals might have contributed to the decreasing trend of infection
 Anwer Khan Modern Medical College Journal Vol. 10, No. 2: July 2019, P 121-124

Is There Decreasing Prevalence of Helicobacter Pylori Infection in Patients with Dyspepsia?

“…11,16 In a retrospective hospital-based study among dyspeptic patients H. pylori infection rate was 23% (By UBT) during the years of 2015-2018. 18 Stool antigen specifically detects current ifection, whereas serological study detects both past and current infectin. 21,22 Despite this, prevalence of H. pylori infection was similar in the study conducted in 1995 (Serology based) and 2005 (Stool antigen based) (92% vs. 92.7%).…”