Decompressive craniectomy in traumatic brain injury: the randomized multicenter RESCUEicp study (www.RESCUEicp.com)

Hutchinson, Peter J.; Corteen, Elizabeth A.; Czosnyka, Marek; Mendelow, A. D.; Menon, David; Mitchell, Philip B.; Murray, Graham K.; Pickard, John D.; Rickels, E.; Sahuquillo, Juan; Servadei, Franco; Teasdale, G. M.; Timofeev, Ivan; Unterberg, Andreas; Kirkpatrick, Peter J.

doi:10.1007/3-211-30714-1_4

Cited by 251 publications

(151 citation statements)

References 7 publications

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“…Many adult trials of decompressive craniectomy following TBI include patients as young as 10 or 15 years old in their protocols, 16,26 demonstrating a failure to disTraumatic brain injury in pediatric patients: evidence for the effectiveness of decompressive surgery tinguish between adult and pediatric populations. However, significant physiological, anatomical, and pathological differences exist between the ages of birth and adulthood, resulting in the need for clear definitions in patient populations.…”

Section: Physiologymentioning

confidence: 99%

Traumatic brain injury in pediatric patients: evidence for the effectiveness of decompressive surgery

Appelboom

Zoller

Piazza

et al. 2011

FOC

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Traumatic brain injury (TBI) is the current leading cause of death in children over 1 year of age. Adequate management and care of pediatric patients is critical to ensure the best functional outcome in this population. In their controversial trial, Cooper et al. concluded that decompressive craniectomy following TBI did not improve clinical outcome of the analyzed adult population. While the study did not target pediatric populations, the results do raise important and timely clinical questions regarding the effectiveness of decompressive surgery in pediatric patients. There is still a paucity of evidence regarding the effectiveness of this therapy in a pediatric population, and there is an especially noticeable knowledge gap surrounding age-stratified interventions in pediatric trauma. The purposes of this review are to first explore the anatomical variations between pediatric and adult populations in the setting of TBI. Second, the authors assess how these differences between adult and pediatric populations could translate into differences in the impact of decompressive surgery following TBI.

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Section: Physiologymentioning

confidence: 99%

Traumatic brain injury in pediatric patients: evidence for the effectiveness of decompressive surgery

Appelboom

Zoller

Piazza

et al. 2011

FOC

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“…This results in a dramatic reduction in the ICP and a reversal in the clinical and radiological signs of herniation [1] The concept of surgical expansion of the cranial cavity was fi rst expounded by Cushing, who used the procedure for the management of ICP due to brain tumors [2]. There has been a resurgence of interest in decompressive craniectomy for TBI in the past decade [3]. Decompressive craniectomy has also been described for ischemic infarcts and is a standard part of the armamentarium in the management of malignant MCA (middle cerebral artery) infarcts and in cerebral venous thrombosis, where the swollen infract and the surrounding brain acts as a mass lesion [4].…”

Section: Discussionmentioning

confidence: 99%

Decompressive craniectomy: an effective but underutilized option for intracranial pressure management

Mathai

Sahoo²

2008

Indian J Surg

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Introduction Decompressive Craniectomy is an effective option in the management of intractable intracranial hypertension. Aim and objectives Neuronal conservation can be achieved by aggressive decompression (hemicraniectomy).Material and methods In this series 12 patients with a Glasgow Coma Scale score of 8 or <8 with increased intracranial pressure underwent decompressive hemicraniectomy.Results The outcomes were prospectively evaluated. Eight patients were victims of traumatic brain injury. There were two patients who had suffered malignant Middle Cerebral Artery Infarctions, one patient had a cerebral venous thrombosis and one, an intracerebral hematoma. Four patients in this cohort died, while fi ve had good outcomes. ConclusionThe rationale and role of this relatively easy but underutilised procedure are discussed.

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“…It is accompanied by a large dural opening (dural flap pedicles are based on the superior sagittal sinus medially, and also a division of the falx anteriorly is required). The primary endpoint of the Rescue-ICP study will be the outcome assessment at discharge (GOS score), and then at six months after injury (Extended GOS score), while secondary www.intechopen.com endpoints will be: a) the assessment of outcome using the SF-36 and the SF-10 questionnaires, b) assessment of ICP control, c) length of stay in the ICU, d) hospital length of stay, and e) a detailed health-economic analysis of the collected data [Hutchinson, et al, 2006 ]. The results of the Rescue-ICP study are expected with great interest, and may greatly influence the future of DC and the overall management of patients suffering S-TBIs.…”

Section: The Rescue Icp Trialmentioning

confidence: 99%

The Role of Decompressive Craniectomy in the Management of Patients Suffering Severe Closed Head Injuries

Gatos¹,

Kapsalaki²,

Paterakis³

et al. 2012

Brain Injury - Pathogenesis, Monitoring, Recovery and Management

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Decompressive craniectomy in traumatic brain injury: the randomized multicenter RESCUEicp study (www.RESCUEicp.com)

Cited by 251 publications

References 7 publications

Traumatic brain injury in pediatric patients: evidence for the effectiveness of decompressive surgery

Traumatic brain injury in pediatric patients: evidence for the effectiveness of decompressive surgery

Decompressive craniectomy: an effective but underutilized option for intracranial pressure management

The Role of Decompressive Craniectomy in the Management of Patients Suffering Severe Closed Head Injuries

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