Decontamination of a field laboratory dedicated to Ebola virus–infected patients

Gaillard, Tiphaine; Delaune, D.; Flusin, Olivier; Paucod, Jean-Charles; Richard, Stéphane; Boubis, Laetitia; Honeywood, Yan; Janvier, Frédéric; Foissaud, Vincent; Thibault, François M.; Valade, Eric; Mérens, Audrey

doi:10.1016/j.ajic.2016.05.034

Cited by 3 publications

(1 citation statement)

References 6 publications

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“…The caregiver treatment centre offered conditions for the care and study of Ebola virus–infected patients never previously available in developing countries or in an epidemic context. That has allowed a number of clinical, pathophysiologic, therapeutic, diagnostic and epidemiologic studies to provide original and valuable results [59] , [60] , [61] , [62] .…”

Section: Discussionmentioning

confidence: 99%

Contribution of the French army health service in support of expertise and research in infectiology in Africa

Pradines

Rogier²

2018

New Microbes and New Infections

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Historically, infectious diseases have caused more casualties than battle. The French military health service therefore developed a range of research on vector-borne diseases such as malaria and arboviruses, antibiotic resistance, infectious agents that can be used as biological weapons and vaccines. The main objective is to control naturally acquired or provoked infectious diseases and limit their impact on armed forces as well as on civilian populations in France or abroad, particularly in Africa and anywhere French armies may be deployed. The expertise of the military health service teams in manipulating agents requiring high level of biosafety precautions and in organizing and providing medical care in unnatural conditions, including the battlefield, associated with complementarity staff experience (physicians, biologists, epidemiologists, researchers, pharmacists, logisticians), has been used in the management of the Ebola outbreak in Guinea.

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Section: Discussionmentioning

confidence: 99%

Contribution of the French army health service in support of expertise and research in infectiology in Africa

Pradines

Rogier²

2018

New Microbes and New Infections

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Ebola virus disease: Biological and diagnostic evolution from 2014 to 2017

Mérens

Bigaillon

Delaune

2018

Médecine et Maladies Infectieuses

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Existing operational standards for field deployments of rapid response mobile laboratories: a scoping review

Mushasha,

Paez Jimenez,

Dolmazon

et al. 2024

Front. Public Health

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IntroductionRapid response mobile laboratories (RRML) play an important role in responding to emergencies such as outbreaks and humanitarian crises, working in coordination with national authorities. This scoping review aims to provide evidence to support the development of minimum operational standards for the deployment of RRMLs across the five key workstreams: operational support and logistics, biosafety and biosecurity, laboratory information management system, quality management systems and interoperability and coordination.MethodsWe searched PubMed, MEDLINE, EMBASE and the grey literature focusing on RRML deployment missions. Study characteristics such as year, country, objectives, methods, and findings were extracted and summarized to identify common themes, gaps, and patterns. The results were presented in a narrative format. We ensured methodological rigor by following the Preferred Reporting Items for Systematic Reviews and Meta-Analyses extension for Scoping Reviews (PRISMA-ScR) guidelines throughout the review process.ResultsOut of 163 full-text studies assessed for eligibility, 46 met the inclusion criteria and were analyzed. Six studies addressed the five RRML workstreams. Operational support and logistics are most commonly addressed during pre-deployment phases with a focus on personnel, transport and cold chain management. The application of biosafety and biosecurity protocols is most addressed during the mission execution phase, particularly in the use of personal protective equipment and the implementation of decontamination and disinfection procedures. The laboratory information management system procedures most frequently reported include sample identification and result dissemination protocols. The quality management system workstream overlaps significantly with the other four workstreams, with a strong emphasis on internal and external quality assurance measures. Coordination and interoperability aspects involve maintaining multiple collaborations, ranging from coordinating with local authorities to establishing international partnerships. Common field challenges included interrupted data transfer in areas characterized by poor connectivity and difficulties caused by extreme weather conditions.DiscussionThis review highlights RRML deployment procedures and addresses some critical challenges concerning their deployment. It suggests the provision of a pre-deployment logistics checklist, the use of a pre-determined standardized dataset for inputs to reduce data entry errors and the application of standardized internal and external quality assurance measures.

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Decontamination of a field laboratory dedicated to Ebola virus–infected patients

Cited by 3 publications

References 6 publications

Contribution of the French army health service in support of expertise and research in infectiology in Africa

Contribution of the French army health service in support of expertise and research in infectiology in Africa

Ebola virus disease: Biological and diagnostic evolution from 2014 to 2017

Existing operational standards for field deployments of rapid response mobile laboratories: a scoping review

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