Deconvolution of 40 Hz steady-state fields reveals two overlapping source activities of the human auditory cortex

Gutschalk, Alexander; Mase, Ryuzo; Roth, Rainer; Ille, Nicole; Rupp, André; Hähnel, Stefan; Picton, Terence W.; Scherg, Michael

doi:10.1016/s1388-2457(99)00019-x

Cited by 165 publications

(123 citation statements)

References 56 publications

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“…An origin of the steady-state activities in two foci of the HG is consistent with previous magnetoencephalographic (MEG) (Gutschalk et al, 1999) and intracranial EEG (Liegeois-Chauvel et al, 2004) studies.…”

Section: Attentional Modulation Of Ssrssupporting

confidence: 88%

Effects of Selective Attention on the Electrophysiological Representation of Concurrent Sounds in the Human Auditory Cortex

Bidet-Caulet

Fischer²,

Besle³

et al. 2007

J. Neurosci.

204

173

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In noisy environments, we use auditory selective attention to actively ignore distracting sounds and select relevant information, as during a cocktail party to follow one particular conversation. The present electrophysiological study aims at deciphering the spatiotemporal organization of the effect of selective attention on the representation of concurrent sounds in the human auditory cortex. Sound onset asynchrony was manipulated to induce the segregation of two concurrent auditory streams. Each stream consisted of amplitude modulated tones at different carrier and modulation frequencies. Electrophysiological recordings were performed in epileptic patients with pharmacologically resistant partial epilepsy, implanted with depth electrodes in the temporal cortex. Patients were presented with the stimuli while they either performed an auditory distracting task or actively selected one of the two concurrent streams. Selective attention was found to affect steady-state responses in the primary auditory cortex, and transient and sustained evoked responses in secondary auditory areas. The results provide new insights on the neural mechanisms of auditory selective attention: stream selection during sound rivalry would be facilitated not only by enhancing the neural representation of relevant sounds, but also by reducing the representation of irrelevant information in the auditory cortex. Finally, they suggest a specialization of the left hemisphere in the attentional selection of fine-grained acoustic information.

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Section: Attentional Modulation Of Ssrssupporting

confidence: 88%

Effects of Selective Attention on the Electrophysiological Representation of Concurrent Sounds in the Human Auditory Cortex

Bidet-Caulet

Fischer²,

Besle³

et al. 2007

J. Neurosci.

204

173

View full text Add to dashboard Cite

show abstract

“…Like many previous M/EEG, intracranial, and lesioneffect studies, our data clearly implicate primary auditory cortex as the main generator of the MLR (Celesia 1976;Kraus et al 1982;Özdamar et al 1982;Scherg and Von Cramon 1986;Liégeois-Chauvel et al 1994;Hashimoto et al 1995;Kuriki et al 1995;Gutschalk et al 1999;Godey et al 2001;Rupp et al 2002b;Yvert et al 2005;Parkkonen et al 2009). Lateralization of the MLR in response to monaural stimulation, however, has historically been controversial, with some EEG studies reporting lateralization (Woods and Clayworth 1985;Woods et al 1987;Cacace et al 1990;Kaseda et al 1991) and others reporting balance (Peters and Mendel 1974;Scherg and Von Cramon 1986;Kileny et al 1987;Jacobson and Grayson 1988).…”

Section: Generators and Lateralization Of The Mlrsupporting

confidence: 88%

“…Lateralization of the MLR in response to monaural stimulation, however, has historically been controversial, with some EEG studies reporting lateralization (Woods and Clayworth 1985;Woods et al 1987;Cacace et al 1990;Kaseda et al 1991) and others reporting balance (Peters and Mendel 1974;Scherg and Von Cramon 1986;Kileny et al 1987;Jacobson and Grayson 1988). Consistent with human intracranial recordings (Celesia 1976), MEG has shown lateralization, both of the P30 Yvert et al 2001) and the related auditory steady-state response (ASSR) (Ross et al 2005;Gutschalk et al 2012), which reflects overlapping middle-latency responses (Gutschalk et al 1999;Bohórquez and Ozdamar 2008).…”

Section: Generators and Lateralization Of The Mlrmentioning

confidence: 99%

Lateralization and Binaural Interaction of Middle-Latency and Late-Brainstem Components of the Auditory Evoked Response

Dykstra

Burchard

Starzynski

et al. 2016

JARO

Self Cite

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We used magnetoencephalography to examine lateralization and binaural interaction of the middlelatency and late-brainstem components of the auditory evoked response(the MLR and SN10, respectively). Click stimuli were presented either monaurally, or binaurally with left-or right-leading interaural time differences (ITDs). While early MLR components, including the N19 and P30, were larger for monaural stimuli presented contralaterally (by approximately 30 and 36% in the left and right hemispheres, respectively), later components, including the N40 and P50, were larger ipsilaterally. In contrast, MLRs elicited by binaural clicks with left-or right-leading ITDs did not differ. Depending on filter settings, weak binaural interaction could be observed as early as the P13 but was clearly much larger for later components, beginning at the P30, indicating some degree of binaural linearity up to early stages of cortical processing. The SN10, an obscure late-brainstem component, was observed consistently in individuals and showed linear binaural additivity. The results indicate that while the MLR is lateralized in response to monaural stimuli-and not ITDs-this lateralization reverses from primarily contralateral to primarily ipsilateral as early as 40ms post stimulus and is never as large as that seen with fMRI.

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“…To access peripheral effects, we used dis-tortion product otoacoustic emissions (DPOAE) to reveal the cochlear activation state (Kemp, 2007). Simultaneously, we measured neuronal activity by electroencephalography (EEG) and analyzed the auditory steady-state response (ASSR) as a marker of processing in the primary auditory cortex (Gutschalk et al, 1999;Engelien et al, 2000). Furthermore, we investigated oscillatory neuronal activity (alpha-band activity), which might reflect the impact of attentional processes at higher cortical levels (Foxe and Snyder, 2011;Klimesch, 2012).…”

Section: Introductionmentioning

confidence: 99%

Attentional Modulation of the Inner Ear: A Combined Otoacoustic Emission and EEG Study

Wittekindt

Kaiser

Abel

2014

Journal of Neuroscience

103

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Attending to a single stimulus in a complex multisensory environment requires the ability to select relevant information while ignoring distracting input. The underlying mechanism and involved neuronal levels of this attentional gain control are still a matter of debate. Here, we investigated the influence of intermodal attention on different levels of auditory processing in humans. It is known that the activity of the cochlear amplifier can be modulated by efferent neurons of the medial olivocochlear complex. We used distortion product otoacoustic emission (DPOAE) measurements to monitor cochlear activity during an intermodal cueing paradigm. Simultaneously, central auditory processing was assessed by electroencephalography (EEG) with a steady-state paradigm targeting early cortical responses and analysis of alpha oscillations reflecting higher cognitive control of attentional modulation. We found effects of selective attention at all measured levels of the auditory processing: DPOAE levels differed significantly between periods of visual and auditory attention, showing a reduction during visual attention, but no change during auditory attention. Primary auditory cortex activity, as measured by the auditory steady-state response (ASSR), differed between conditions, with higher ASSRs during auditory than visual attention. Furthermore, the analysis of cortical oscillatory activity revealed increased alpha power over occipitoparietal and frontal regions during auditory compared with visual attention, putatively reflecting suppression of visual processing. In conclusion, this study showed both enhanced processing of attended acoustic stimuli in early sensory cortex and reduced processing of distracting input, both at higher cortical levels and at the most peripheral level of the hearing system, the cochlea.

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Deconvolution of 40 Hz steady-state fields reveals two overlapping source activities of the human auditory cortex

Cited by 165 publications

References 56 publications

Effects of Selective Attention on the Electrophysiological Representation of Concurrent Sounds in the Human Auditory Cortex

Effects of Selective Attention on the Electrophysiological Representation of Concurrent Sounds in the Human Auditory Cortex

Lateralization and Binaural Interaction of Middle-Latency and Late-Brainstem Components of the Auditory Evoked Response

Attentional Modulation of the Inner Ear: A Combined Otoacoustic Emission and EEG Study

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