Deconvolution of the Functional Ultrasound Response in the Mouse Visual Pathway Using Block-Term Decomposition

Abstract

Functional ultrasound (fUS) indirectly measures brain activity by recording changes in cerebral blood volume and flow in response to neural activation.Conventional approaches model such functional neuroimaging data as the convolution between an impulse response, known as the hemodynamic response function (HRF), and a binarized representation of the input (i.e., source) signal based on the stimulus onsets, the so-called experimental paradigm (EP). How-