Decrease in quality of life predicts mortality in adult patients with pulmonary arterial hypertension due to congenital heart disease

Blok, Ilja M.; Riel, Annelieke C.M.J. van; Schuuring, Mark J.; Duffels, Marielle G.; Vis, Jeroen C.; Dijk, Arie P.J. van; Hoendermis, Elke S.; Mulder, Barbara J.M.; Bouma, Berto J.

doi:10.1007/s12471-015-0666-9

Cited by 32 publications

(21 citation statements)

References 31 publications

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“…Yet, health-related quality of life questionnaires provide valuable information on the burden of pulmonary arterial hypertension on the patient's day-to-day living and have also been associated with prognosis. 39,40 In our study, the generic SF-36 and pulmonary hypertensionspecific CAMPHOR questionnaires presented strong inter-domain correlations as observed previously in patients with pulmonary hypertension 41 and were strongly associated with therapeutic objectives as assessed by NYHA functional class and the 6-minute walk distance, supporting their use in clinical practice.…”

Section: Discussionsupporting

confidence: 85%

Health-related quality of life of patients with pulmonary arterial hypertension associated with CHD: the multicentre cross-sectional ACHILLE study

Amedro

Basquin

Gressin³

et al. 2016

Cardiol Young

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Section: Discussionsupporting

confidence: 85%

Health-related quality of life of patients with pulmonary arterial hypertension associated with CHD: the multicentre cross-sectional ACHILLE study

Amedro

Basquin

Gressin³

et al. 2016

Cardiol Young

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“…Quantitative measurement of HRQOL is heavily dependent on patient reported questionnaires and in the field of PAH the use of the SF-36 questionnaire is limited to a few studies ( Chua et al, 2006 ; Taichman et al, 2005 ; Zlupko et al, 2008 ). More recently in a subgroup of patients PAH due to congenital heart disease it was found that a decrease in physical aspects of HRQOL may be a determinant of mortality ( Blok et al, 2015 ).…”

Section: Discussionmentioning

confidence: 99%

Dyspnea, depression and health related quality of life in pulmonary arterial hypertension patients

Talwar

Sahni

Kim³

et al. 2015

J Exerc Rehabil

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Pulmonary arterial hypertension (PAH) is a rare and devastating disease which is characterized by worsening dyspnea and exercise tolerance. These patients are often found to have concomitant, depression, anxiety and impaired health-related quality of life (HRQOL). The interrelationship of dyspnea, depression and HRQOL in these patients is not well studied. Retrospective analysis was performed on 46 PAH patients (mean age 51.73). Patients completed Medical Outcomes Study Short - Form 36 V2 (SF-36) to measure HRQOL, Modified Medical Research Council (mMRC) Dyspnea Scale and Zung Depression Scale (ZDS). Physical Health Composite Scores (PCS) and Mental Health Composite Scores (MCS) were derived from SF-36. Spearman’s correlation was computed to determine degree of correlation between pairs of scales. 46 patients (12 males, 34 females; median age 51.4 yr) with confirmed PAH were considered for the study of which 36 patients (9 males, 27 females, median age 50.1 yr), were eligible for further analysis. MMRC Dyspnea Scale Score was 1.0 (Q1 to Q3:1.0 to 2.0). Median MCS was 52.1 (Q1 to Q3:41.7 to 57.1) and PCS was 37.9 (Q1 to Q3: 30.7 to 49.6). There was a significant negative correlation between dyspnea and PCS (r =−0.660, P<0.0001) and MCS (r =−0.342, P<0.0411). The ZDS was available for 17 of these patients; their median score was 42.0 (Q1 to Q3: 33.0 to 46.0). There was a significant correlation between the ZDS and PCS (r =−0.578, P<0.0150,) MCS (r =−0.752, P<0.0005). Patients with PAH suffer from diminished HRQOL correlating with their dyspnea and underlying depression.

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“…[6]). Assessing quality of life can be beneficial in medical practice; allowing an individual to self-assess their health status has shown to be a strong indicator and predictor of mortality [7, 8]. Additionally, by assessing the subjective effect of living with a disease or disability it is possible to identify high risk groups at which to target health interventions, to improve quality of life and satisfaction of intervention protocols [9].…”

Section: Introductionmentioning

confidence: 99%

A survey of the impact of owning a service dog on quality of life for individuals with physical and hearing disability: a pilot study

Hall

MacMichael

Turner

et al. 2017

Health Qual Life Outcomes

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BackgroundQuality of life refers to a person’s experienced standard of health, comfort and happiness and is typically measured using subjective self-report scales. Despite increasing scientific interest in the value of dogs to human health and the growing demand for trained service dogs, to date no research has reported how service dogs may affect client perceptions of quality of life.MethodWe compared quality of life scores on the 16 item Flanagan quality of life scale from individuals who owned a trained service dog with those who were eligible to receive a dog, but did not yet have one (waiting list control). Data were analysed separately from two groups; those with a service dog trained for individuals with physical disabilities (with physical service dog: n = 72; waiting for a service dog: n = 24; recruited from Dogs for Good database) and those with a hearing service dog (with hearing service dog = 111; waiting for a service dog = 30; recruited from Hearing Dogs for Deaf People database).ResultsWhen controlling for age and gender individuals scored higher on total quality of life scores if they owned a service dog or a hearing service dog, but this was only statistically significant for those with a service dog. Both groups (physical service dog and hearing service dog) scored significantly higher on items relating to health, working, learning and independence if they owned a service dog, in comparison to those on the waiting list. Those with a physical service dog also scored significantly higher on items relating to recreational activities (including items relating to reading/listening to music, socialising, creative expression), and those involving social interactions (including items relating to participating in organisations, socialising, relationship with relatives). Additionally, those with a physical service dog scored higher on understanding yourself and material comforts than those on the waiting list control. In contrast, those with a hearing service dog appeared to receive fewer benefits on items relating to social activities.ConclusionsOwning a service dog can bring significant specific and potentially general benefits to the quality of life of individuals with physical disabilities and hearing impairments. These benefits may have considerable implications for individuals with disabilities, society and the economy by promoting independence, learning and working abilities.

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Decrease in quality of life predicts mortality in adult patients with pulmonary arterial hypertension due to congenital heart disease

Cited by 32 publications

References 31 publications

Health-related quality of life of patients with pulmonary arterial hypertension associated with CHD: the multicentre cross-sectional ACHILLE study

Health-related quality of life of patients with pulmonary arterial hypertension associated with CHD: the multicentre cross-sectional ACHILLE study

Dyspnea, depression and health related quality of life in pulmonary arterial hypertension patients

A survey of the impact of owning a service dog on quality of life for individuals with physical and hearing disability: a pilot study

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