Decrease in serum LDL cholesterol with microcrystalline chitosan in healthy subjects

Adsorption of lipoproteins with the aid of carboxymethylchitosan mircrospheres crosslinked with poly(ethylene glycol) bisglycidyl ether

“…Because of its excellent properties such as biocompatibility, biodegradability and antimicrobiality, chitosan has been used as food packing materials (Arvanitoyannis, 1999), biomedical engineering scaffolds (Hsieh, Chang, & Lin, 2007;Kim et al, 2008). Chitosan is also used as a dietary fiber (Hossain et al, 2007;Xu, Huang, Qiu, Wu, & Hu, 2007) or a potential medicine against hypercholesterolemia (Lehtimäiki, Wuolijoki, Hirvelä, Lehtinen, & Ylitalo, 1995) because it can either adsorb cholesterolemia in the food or interact by electrostatic force with fatty acid and bile acid which have negative charge, in the digestive tract (Yao, Huang, & Chiang, 2008).…”