Decrease of blue cone sensitivity in acute idiopathic blind spot enlargement syndrome

Chan

Survey of Ophthalmology

et al. 2007

Abstract. Multifocal electroretinography (mfERG) is an investigation that can simultaneously measure multiple electroretinographic responses at different retinal locations by cross-correlation techniques. mfERG therefore allows topographic mapping of retinal function in the central 40--50 of the retina. The strength of mfERG lies in its ability to provide objective assessment of the central retinal function at different retinal areas within a short duration of time. Since the introduction of mfERG in 1992, mfERG has been applied in a large variety of clinical settings. This article reviews the clinical applications of mfERG based on the currently available evidence. mfERG has been found to be useful in the assessment of localized retinal dysfunction caused by various acquired or hereditary retinal disorders. The use of mfERG also enabled clinicians to objectively monitor the treatment outcomes as the changes in visual functions might not be reflected by subjective methods of assessment. By changing the stimulus, recording, and analysis parameters, investigation of specific retinal electrophysiological components can be performed topographically. Further developments and consolidations of these parameters will likely broaden the use of mfERG in the clinical setting.

Section: Acute Idiopathic Blind Spot Enlargement Syndrome (Aibse)mentioning

confidence: 99%

The Clinical Applications of Multifocal Electroretinography: A Systematic Review

Chan

Survey of Ophthalmology

et al. 2007

“…For instance, Johnson et al and Sample et al have reported that SWAP deficits are predictive of impending glaucomatous VF loss for standard WW perimetry in their longitudinal studies using ocular hypertensive and glaucomatous eyes 13,18 . Additionally, Machida et al suggested that blue cone pathways may be more delicate and susceptible to photoreceptor diseases 53 . The response range of these cones is also significantly limited compared with the other cones, hence an equivalent loss of function among the cone cells would result in a larger response in the blue cone pathway 53 .…”

Section: Discussionmentioning

confidence: 99%

Short wavelength automated perimetry and standard automated perimetry in central serous chorioretinopathy

Zhou

Asaoka

Inoue

et al. 2020

Sci Rep

Short wavelength automated perimetry (SWAP) is known for detecting the early reduction of retinal sensitivity (RS) in glaucoma. It’s application in retinal diseases have also been discussed previously. We investigated the difference in RS measured between standard white-on-white automated perimetry (WW) and blue-on-yellow SWAP in central serous chorioretinopathy (CSC). The overall RS (W-RS, S-RS) as well as the RS inside and outside of the serous retinal detachment (SRD) region were investigated in 26 eyes of 26 CSC patients using WW and SWAP. The central retinal thickness, central choroidal thickness, SRD area (SRDa), and SRD height at the fovea were measured using optic coherence tomography. RS inside the SRD region was lower than that of outside for both perimetries (both p < 0.001). The difference between RS inside and outside of the SRD region was greater in SWAP compared to WW (p < 0.001). Univariate analysis revealed significant correlations between SRDa and both W-RS and S-RS (both p < 0.001); moreover, multivariate analysis indicated that only S-RS was selected as the optimal model for SRDa. Our study demonstrated that SWAP was detected the decrease in RS more accurately than WW in CSC. These results may suggest the usefulness of SWAP for detecting change of retinal function in CSC.

“…Machida et al9 reported on their evaluation of a patient with acute idiopathic blind-spot enlargement syndrome who was evaluated using both white-on-white and blue-on-yellow perimetry. The difference in the mean deviation was significantly greater for blue-on-yellow perimetry as compared with white-on-white perimetry.…”

Section: Discussionmentioning

confidence: 99%

“…First, blue cones may be more delicate physiologically and more susceptible to photoreceptor diseases 9. Second, the response range over which the blue cone functions is significantly limited compared with those of the other cones.…”

Section: Discussionmentioning

confidence: 99%

“…The utility of blue-on-yellow perimetry has been discussed in connection with other retinal diseases such as age-related macular disease, night blindness, and idiopathic blind spot enlargement syndrome 1,7–9. To my knowledge, few reports have investigated the utility of blue-on-yellow perimetry in the treatment of neuro-ophthalmological disorders 1,10–14.…”

Section: Introductionmentioning

confidence: 99%

See 1 more Smart Citation

Utility of blue-on-yellow perimetry in the evaluation of patients with idiopathic optic neuropathy

Makino

2013

OPTH

A 68-year-old woman with bilateral idiopathic optic neuropathy was examined using blue-on-yellow perimetry. Best-corrected visual acuity was 0.5 and 0.6 in her right and left eyes, respectively. Visual field testing with a Goldmann perimeter showed constriction of the I/2 e isopter in both eyes. With regard to mean deviation, the results (−13.18 dB right, −10.01 dB left) of blue-on-yellow perimetry were worse than those obtained using white-on-white perimetry (−1.26 dB right, −1.83 dB left). Optical coherence tomography revealed decreased retinal nerve fiber layer thickness in both eyes. Blue-on-yellow perimetry is useful for the detection of visual field disturbances in patients with optic neuropathy.