Decrease of respiratory events in patients with obstructive sleep apnea-hypopnea syndrome using a mandibular advancement device assessed with split night polysomnography

Abstract

IntroductionMandibular advancement device (MAD) may represent a feasible choice in the treatment of obstructive sleep apnea-hypopnea syndrome (OSAHS), in well selected patients.ObjectiveThe aim of this study is to assess the efficacy of MAD in patients with OSAHS, using split night polysomnography (SNP)MethodWe performed an auto controlled clinical trial to assess the efficacy of MAD in 30 patients with snoring and OSAHS. Clinical evaluation was made every 2 weeks to adjust treatment and observe changes in clinical symptoms. Three-months after placement of the MAD, a SNP was performed, using the MAD in the second half of the night, in order to compare the respiratory results.ResultsSNP show significant changes with use of MAD (p<0.05) such as: Decrease in Snore index (from 159.95 to 32.46/h) and in Apnea-hypopnea index (AHI, from 22.45 to 4.63/h), increase in oxygen saturation (SaO2, from 89.98% to 91.39%) and somnolence improvement, using the Epworth Sleepiness Scale (from 14.4 to 4.6 points).ConclusionOur data supports that the use of MAD is an alternative in the management of OSAHS, in well selected patients, used in a multidisciplinary fashion, and evaluated using a SNP.

Use Of Mandibular Advancement Devices For Obstructive Sleep Apnoea Treatment In Adults

“…A recent paper revealed similar data with significant changes in Snore index, Apnea-hypopnea index, oxygen saturation and sleepiness (Epworth Sleepiness Scale) [39]. Improvements in cognitive performace and quality of life, as well as a reduction in risk of cardiovascular events, were also observed in the present study.…”

“…One month after MAD collocation, patients were asked about the event of side effects for the use of MAD. Three months after MAD collocation, once the patient and his bed partner reported an evident clinical improvement, the next step is the polysomnography evaluation with MAD at the adequate advancement level [39].…”

Obstructive sleep apnea syndrome among obese individuals: A cross-sectional study

“…After analyzing the data, OSAS is classified according to the number of respiratory events and the apnea--hypopnea index (AHI): it is considered mild when 5 to 15 events/hour are recorded; moderate is 15 to 30 events/hour; and severe is a mean of ≥ 30 events/hour. [5][6][7][8][9][10][11] Individuals may have distinct symptoms, namely excessive daytime sleepiness, depressive states, impaired memory and learning abilities, poor concentration and attention span, and cardiovascular diseases, which can culminate in sudden death. OSAS is a progressive chronic disease that directly influences quality of life, given that sleep is a brain function that is essential to life and aids in relieving human stress.…”

Application of Polysomnography in Nursing Care of Patients with OSAHS

“…OSAHS is a common disease in respiratory medicine [10]. When sleeping at night, intermittent apnea leads to hypoxia of patients, reduces sleep quality, and affects their normal work and life [11].…”