Decrease of the foveal avascular zone area after internal limiting membrane peeling: single case study

Kumagai, Kazuyuki; Uemura, Akinori; Furukawa, Masao; Suetsugu, Tetsuyuki; Ogino, Nobuchika

doi:10.2147/imcrj.s129174

Cited by 7 publications

(5 citation statements)

References 17 publications

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“…The area of FAZ is correlated with sex, age, and foveal thickness [ 11 ]. The effect of ILM peeling on FAZ is well known [ 12 , 13 , 14 , 15 ]. In the present study, FAZ area in the ERM group was significantly smaller than that in the control group.…”

Section: Discussionmentioning

confidence: 99%

Idiopathic Epiretinal Membrane: Microvasculature Analysis with Optical Coherence Tomography and Optical Coherence Tomography Angiography

et al. 2022

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Background: The present study examined the relationships among macular microvasculature, retinal structure, and epiretinal membrane (ERM) and explored the utility of optical coherence tomography (OCT) angiography (OCTA) in idiopathic ERM assessment. Methods: The study sample comprised 276 eyes of 276 patients. A total of 154 eyes with ERM and 122 normal (control) eyes were analyzed. Only one eye of each participant was randomly selected for posterior segment imaging. Each patient underwent OCT and OCTA. Images were analyzed with AngioTool 0.6. Results: Foveal avascular zone was significantly smaller in the ERM group (p = 0.044). Average retinal thickness and foveal thickness were significantly higher in the ERM group (both p = 0.001). Moreover, 64 (41.5%) patients exhibited no metamorphopsia, while 46 (29.8%) and 44 (28.7%) patients exhibited moderate and extensive metamorphopsias, respectively. Meanwhile, FAZ was negatively correlated with central retinal thickness in the ERM group. The vessel area (p = 0.0017) and vessel percentage area (p = 0.044) were significantly greater in the ERM group. Conclusions: Changes observed in the superficial plexus in OCTA are related to the severity of metamorphopsia and can be further evaluated to support decision making regarding the surgical management of idiopathic ERM.

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Section: Discussionmentioning

confidence: 99%

Idiopathic Epiretinal Membrane: Microvasculature Analysis with Optical Coherence Tomography and Optical Coherence Tomography Angiography

et al. 2022

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“…We have reported two cases that showed a decrease in the FAZ area and the papillofoveal distance after vitrectomy with ILM peeling for a VMT and thin ERM. 11 , 12 In this study, we compared the decrease of the FAZ area and papillofoveal distance with or without ILM peeling. A significant decrease in the FAZ area and papillofoveal distance was observed postoperatively only in the ILM-peeled eyes.…”

Section: Discussionmentioning

confidence: 99%

“… 16 Recently, we have reported that the course of the postoperative decrease of the FAZ area could be fit by a hyperbolic curve in one case. 12 However, the mechanism was not determined, and we did not try to find other equations that might suit our data. In this study, we added five additional cases, and our analysis showed that the course of the postoperative decrease of the FAZ area could be fit by a hyperbolic curve ( R 2 =0.969–0.998; n=6).…”

Section: Discussionmentioning

confidence: 99%

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Early centripetal displacements of capillaries in macular region caused by internal limiting membrane peeling

Kumagai¹,

Ogino²,

Furukawa³

et al. 2018

OPTH

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PurposeThe aim of this study was to determine whether the centripetal displacement of the capillaries in the macular region after vitrectomy is caused by internal limiting membrane (ILM) peeling.MethodsEighteen patients with different types of retinal diseases but with a normal or approximately normal foveal contour underwent successful vitrectomy with (n=12) or without (n=6) ILM peeling. Optical coherence tomography angiography (OCTA) images of the inner retinal vascular plexus in the macular region were analyzed pre- and postoperatively. Four concentric polygonal areas were marked in the OCTA images with the corners selected to be easily identified by vessel bifurcations. The areas of the postoperative foveal avascular zone (FAZ) and the four polygonal regions at about 1 month postoperatively were compared to the baseline areas.ResultsVitrectomy was performed for eleven eyes with vitreomacular tractions, three with macular-on retinal detachments, and four with thin epiretinal membranes. A significant decrease in the FAZ area was observed postoperatively in only the ILM-peeled eyes (P=0.0002). The four polygonal areas in the ILM-peeled eyes decreased after surgery, and the decrease was fit by a linear regression line (R2=0.985–0.999; n=7). The time course of the postoperative decrease of the FAZ area was fit by a hyperbolic curve (R2=0.969–0.998; n=6). The average postoperative time required to reach one-half of the final FAZ area was 1.16 days (0.81–1.62 days).ConclusionThese findings suggest that ILM peeling causes an early centripetal displacement of the capillaries in the macular region.

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“…The decrease in FAZ area suggests that a centripetal movement of retinal layers occurs after ILM peeling. 17 …”

Section: Discussionmentioning

confidence: 99%

Increase in average foveal thickness after internal limiting membrane peeling

Kumagai

Furukawa

Suetsugu

et al. 2017

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PurposeTo report the findings in three cases in which the average foveal thickness was increased after a thin epiretinal membrane (ERM) was removed by vitrectomy with internal limiting membrane (ILM) peeling.MethodsThe foveal contour was normal preoperatively in all eyes. All cases underwent successful phacovitrectomy with ILM peeling for a thin ERM. The optical coherence tomography (OCT) images were examined before and after the surgery. The changes in the average foveal (1 mm) thickness and the foveal areas within 500 μm from the foveal center were measured. The postoperative changes in the inner and outer retinal areas determined from the cross-sectional OCT images were analyzed.ResultsThe average foveal thickness and the inner and outer foveal areas increased significantly after the surgery in each of the three cases. The percentage increase in the average foveal thickness relative to the baseline thickness was 26% in Case 1, 29% in Case 2, and 31% in Case 3. The percentage increase in the foveal inner retinal area was 71% in Case 1, 113% in Case 2, and 110% in Case 3, and the percentage increase in foveal outer retinal area was 8% in Case 1, 13% in Case 2, and 18% in Case 3.ConclusionThe increase in the average foveal thickness and the inner and outer foveal areas suggests that a centripetal movement of the inner and outer retinal layers toward the foveal center probably occurred due to the ILM peeling.

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Decrease of the foveal avascular zone area after internal limiting membrane peeling: single case study

Cited by 7 publications

References 17 publications

Idiopathic Epiretinal Membrane: Microvasculature Analysis with Optical Coherence Tomography and Optical Coherence Tomography Angiography

Idiopathic Epiretinal Membrane: Microvasculature Analysis with Optical Coherence Tomography and Optical Coherence Tomography Angiography

Early centripetal displacements of capillaries in macular region caused by internal limiting membrane peeling

Increase in average foveal thickness after internal limiting membrane peeling

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