Decreased Choline-Esterase Activity of Serum in Jaundice and in Biliary Disease.

Choline Esterase of Blood Cells and Plasma in Blood Dyscrasias, With Special Reference to Pernicious Anemia

“…The values for plasma E were in accord with those reported by others, who have found low esterase in serum of patients who were debilitated or comatose from a variety of causes (3,7). All of the cases with markedly low hematocrit and red count showed low plasma esterase activity.…”

“…It appears from the leukemia picture, however, that this is probably not the explanation. And since low serum esterase has been reported in acute hemolytic icterus (7), in the face of massive blood destruction, it does not seem probable that blood destruction is the mechanism for removing the esterase from the cells into the plasma. How the reduction is controlled and what the mechanism is whereby cells lose and the plasma gains esterase activity are unexplained.…”

Physiological Effects of the Thyroid Hormones

“…The information concerning the effect of thyroid hormones on cholinesterase activity is no less contradictory. An increase in serum cholinesterase activity in hyperthyroidism was observed by Antopol et al [28], Faber [168], and Uono [616]. An increase in cholesterase activity in the liver under the influence of thyroxine was found by Quandramagna et al [488].…”

Poisoning by Meta-Isosystox in Spraymen and in Accidentally Exposed Patients

“…Controls of the same sex, age, and occupation (farnming) and living under the same environmental conditions were examined for two reasons: (1) Other factors might have contributed to a deviation of serum ChE from normal, e.g., low levels were observed in cases of malnutrition (McCance, 1950) and liver disease (Antopol, Schifrin, and Tuchman, 1938). Our patients were farm workers and were prone to tropical diseases, especially bilharziasis.…”