Decreased incidence of intussusception during the COVID-19 pandemic. Trends in pediatric surgical emergencies

Seo, Shogo; Suda, Kazuto; Kato, Hitoshi; Abe, Eri; Kosaka, Seitaro; Fujiwara, Kentaro; Ochi, Takanori; Koga, Hiroyuki; Urao, Masahiko; Okazaki, Tadaharu; Lane, Geoffrey J.; Yamataka, Atsuyuki

doi:10.1007/s00383-021-04992-1

Cited by 8 publications

(8 citation statements)

References 11 publications

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“…Our study also showed that the total number of pediatric visits to EDs and patients with suspected and true intussusception also decreased. Seo S et al also reported a 3-percentage-point reduction in pediatric intussusception patients in 2020, compared to the pre-COVID-19 pandemic period, in an analysis based on data from three hospitals in Tokyo, Japan [ 25 ]. There are two possible reasons for the decrease in the number of pediatric intussusception patients visiting the emergency department.…”

Section: Discussionmentioning

confidence: 99%

Impact of the COVID-19 Pandemic on Emergency Care Utilization and Outcomes in Pediatric Patients with Intussusception

Lee

Kwon

et al. 2022

Children

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Background: We determined whether a decrease in healthcare utilization patterns during the COVID-19 pandemic affected the treatment process of pediatric patients with intussusception. Methods: Patients with suspected intussusception who had ICD-10 code K561 as their discharge diagnosis from the national database were selected, and those who underwent either radiologic and/or surgical reduction were defined as true intussusception patients. We compared the time periods from patients visiting the ED to ultrasound, radiologic reduction and/or surgical reduction between the study group (first half of 2020, COVID-19 period) and the control groups (control group 1: first half of 2019, control group 2: second half of 2019). Results: The number of suspected intussusception patients in each group was 1223, 1576, and 624, and the incidence rates were 7.85, 11.30, and 4.19 per 100,000 person-half-years (control group 1, control group 2, study group, respectively, p < 0.05). No differences in terms of the time from the ED visit to ultrasound, radiological reduction and/or surgical reduction were noted between the study group and the control groups. Conclusions: In Korea, the COVID-19 pandemic did not significantly affect the ED treatment process or the results of patients with intussusception.

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Section: Discussionmentioning

confidence: 99%

Impact of the COVID-19 Pandemic on Emergency Care Utilization and Outcomes in Pediatric Patients with Intussusception

Lee

Kwon

et al. 2022

Children

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“…To the best of our knowledge, there have been no such studies thus far, except for one study on the COVID-19 pandemic and changes in pediatric emergency diseases, including intussusception. 21 This is significant as it is the first study to reveal the impact of infection control measures during the COVID-19 pandemic on the incidence of intussusception.…”

Section: Discussionmentioning

confidence: 99%

Changes in the Incidence of Intussusception and Infectious Diseases After the COVID-19 Pandemic in Korea

Yoo

Jeong

2022

J Korean Med Sci

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Background Intussusception refers to the invagination of a part of the intestine into itself. The exact cause for this condition is unknown in most cases. The active implementation of coronavirus disease 2019 (COVID-19) infection control guidelines has reduced the spread of COVID-19 and the incidence of other infectious diseases in children. The current study aimed to identify changes in pediatric intussusception and infectious diseases after the implementation of infection control guidelines and confirm the association between intussusception and contagious diseases. Methods We analyzed the electronic medical records of pediatric patients diagnosed with intussusception from seven hospitals in Korea between January 2017 and December 2020. We used open data from the Korea Disease Control and Prevention Agency to investigate changes in infectious diseases over the same period. Results Altogether, we evaluated 390 children with intussusception. There was a statistically significant decrease in the incidence of monthly visits with intussusception in the COVID-19 period group (9.0 vs. 3.5, P < 0.001). When the monthly incidence of infectious diseases was compared between the pre-COVID-19 and the COVID-19 periods, a statistically significant decrease in respiratory viruses (7979.0 vs. 815.2, P < 0.001), enterovirus infection (262.2 vs. 6.6, P < 0.001), and viral enteritis (916.2 vs. 197.8, P < 0.001) were confirmed in the COVID-19 period. Through interrupted time series analysis, it was confirmed that the incidence of intussusception and viral infectious diseases have drastically decreased since March 2020, when COVID-19 infection control guidelines were actively implemented. Conclusion We confirmed that implementing infection control guidelines during the COVID-19 pandemic resulted in a decrease in intussusception and viral infectious diseases. Through this result, it was possible to indirectly confirm the existing hypothesis that viral infections play a significant role in the pathophysiologic mechanism of intussusception.

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“…Some later studies also documented that the COVID-19 pandemic and the implementations of preventative measures to combat this communicable disease have notably influenced the epidemiology of intussusception [ 15 , 16 , 17 , 18 ]. Meanwhile, Handa et al demonstrated that social distancing has resulted in a significant decline in intussusception [ 18 ].…”

Section: Discussionmentioning

confidence: 99%

“…The pandemic of COVID-19 has significantly changed the epidemiology of intussusception. Zheng et al in China were the first to report that the number of pediatric patients with intussusception decreased significantly in 2020 [ 14 ], as demonstrated by some recent studies [ 15 , 16 , 17 , 18 ]. Nevertheless, the in-depth influence of the COVID-19 pandemic on the diagnosis and treatment of intussusception for pediatric patients has not been well documented.…”

Section: Introductionmentioning

confidence: 99%

How Does the COVID-19 Pandemic Affect Pediatric Patients with Intussusception Treated by Ultrasound-Guided Hydrostatic Enema Reduction?

Yang

Gou

Wang

et al. 2022

JCM

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Background: The pandemic of COVID-19 has significantly influenced the epidemiology of intussusception. Nevertheless, the effects of the COVID-19 pandemic on the operation of ultrasound-guided hydrostatic enema reduction (USGHER) for intussusception have been largely unknown. Methods: The data of pediatric patients with intussusception who were treated by USGHER from January to March of 2019 (Control Group), 2020 (Study Group 1), and 2021 (Study Group 2) in a large Chinese medical institution were retrospectively collected and analyzed. Results: We enrolled 246 patients, including 90 cases in Control Group, 70 in Study Group 1, and 86 in Study Group 2 (p = 0.042). The time from the onset of symptoms to the hospital visit and the time from the hospital visit to performing the ultrasound in Study Group 1 was significantly longer than that in Control Group and Study Group 2 (p = 0.036, p = 0.031, respectively). The number of patients with bloody stool and the longest invaginated length of intussusception in Study Group 1 increased significantly compared with patients in the other two groups (p = 0.007, p = 0.042, respectively). Comparisons of neither the pressure of enema nor the time of duration when performing USGHER present statistical significance among the three groups (p = 0.091, p = 0.085, respectively). For all enrolled pediatric patients, there was no perforation case involved, and recurrence of intussusception occurred in few cases. Conclusions: Besides the negative impacts on the incidence of intussusception, the COVID-19 pandemic might have led to the diagnostic delay of intussusception and the deterioration of patients’ clinical manifestations, but it did not significantly affect the operation of USGHER and patients’ clinical outcome.

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Decreased incidence of intussusception during the COVID-19 pandemic. Trends in pediatric surgical emergencies

Cited by 8 publications

References 11 publications

Impact of the COVID-19 Pandemic on Emergency Care Utilization and Outcomes in Pediatric Patients with Intussusception

Impact of the COVID-19 Pandemic on Emergency Care Utilization and Outcomes in Pediatric Patients with Intussusception

Changes in the Incidence of Intussusception and Infectious Diseases After the COVID-19 Pandemic in Korea

How Does the COVID-19 Pandemic Affect Pediatric Patients with Intussusception Treated by Ultrasound-Guided Hydrostatic Enema Reduction?

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