Decreased risk of pneumonia in stroke patients receiving acupuncture: A nationwide matched-pair retrospective cohort study

Chang, Chuen Chau; Chen, Ta Liang; Lin, Chao-Shun; Chung, Chi-Li; Yeh, Chun Chieh; Hu, Chaur Jong; Lane, Hsin Long; Liao, Chien Chang; Shih, Chun Chuan

doi:10.1371/journal.pone.0196094

Cited by 14 publications

(11 citation statements)

References 39 publications

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“…Thus, acupuncture-treated stroke patients had a lower risk of pneumonia than those who did not. More randomized control trials are required (Table 1 ) [ 52 ].…”

Section: Reviewmentioning

confidence: 99%

Stroke and Pneumonia: Mechanisms, Risk Factors, Management, and Prevention

Grossmann¹,

Rodriguez²,

Soni³

et al. 2021

Cureus

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A stroke is a cerebrovascular medical emergency characterized by the sudden loss of neurological function due to interruption to the blood supply. A serious and common complication of stroke is pneumonia. This review article outlined various studies in order to understand the pathogenesis pathways that lead to the development of stroke-associated pneumonia, as well as therapeutic and preventive options to reduce pneumonia. The article looked for risk factors that increase the risk of developing pneumonia among stroke patients. In addition, it has reviewed various therapeutic modalities, such as postural modifications, pharmacological treatment, and other unique treatments, in an attempt to find which of them are efficient to decrease the occurrence of pneumonia and which of them are not. The article also attempts to emphasize the importance of early screening for dysphagia among stroke patients and demonstrates the importance of preventive strategies that can be easily implemented, such as routine oral care and behavioral modifications.

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“…Thus, acupuncture-treated stroke patients had a lower risk of pneumonia than those who did not. More randomized control trials are required (Table 1 ) [ 52 ].…”

Section: Reviewmentioning

confidence: 99%

Stroke and Pneumonia: Mechanisms, Risk Factors, Management, and Prevention

Grossmann¹,

Rodriguez²,

Soni³

et al. 2021

Cureus

View full text Add to dashboard Cite

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“…This would also have the advantage of including women and men with a wide range of ages and, therefore, having the potential to evaluate the effects of a CAM at different ages. A good example of this is the cohort study of over 25,000 individuals evaluating whether use of acupuncture after stroke reduced the risk of pneumonia [ 41 ].…”

Section: Discussionmentioning

confidence: 99%

Reproductive outcomes in women and men using complementary and alternative medicine treatment and not receiving artificial reproductive technology: a systematic review

Yogasundram

Hui

Sia

et al. 2020

Arch Gynecol Obstet

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Purpose Infertility is a global problem, but only a minority of couples access assisted reproductive technologies due to financial and sociocultural barriers. Complementary and alternative medicine are seen as another option. We aimed to determine the impact of complementary and alternative medicine on conception, miscarriage and live birth rates in couples not receiving assisted reproductive technology treatments. Methods The electronic databases EMBASE, PubMed, Web of Science and the Allied and Complementary Medicine Database were systematically searched before March 24th 2020. Reference lists of eligible studies were searched for relevant studies. Eligible studies included trials and observational studies that assessed a complementary or alternative medicine and conception, miscarriage or live births in men or women not undergoing fertility treatment. Data were extracted by two independent reviewers using a pre-designed data collection form. The study protocol was published in the PROSPERO database (CRD42018086980). Results Twenty randomized controlled trials were identified, including 2748 individuals. Most studies did not demonstrate any effect of a complementary or alternative medicine on pregnancy, live birth or miscarriage rates. Limited evidence was found for a positive effect of herbal therapies taken by women on conception rates. There was substantial diversity in quality across the studies. Conclusion There is limited evidence of the effectiveness of complementary and alternative medicine on improving the chances of conception and live births, or increasing miscarriage risk. Owing to the generally sub-optimal quality and heterogeneous nature of the evidence, rigorous studies are needed to determine the impact of complementary and alternative medicine on fertility.

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“…The mechanism of AP treatment of PSD is related to the following. AP excites the paralyzed peripheral motor fibers of the medulla oblongata, restores voluntary movement of the glossopharynx, strengthens the blood oxygen supply of the diseased area, improves blood circulation in the motor function area of the cerebral cortex, and promotes the establishment of peripheral blood vessel collateral circulation and nerve cell activation, while strengthening the coordination and compensation between the functional areas of the cortex ( Zhang et al, 2016 ; Li et al, 2017 ; Chang C. C. et al, 2018 ). Cranial diffusion tensor imaging (DTI) and the gold standard TV X-ray swallowing function (VFSS) for the diagnosis of dysphagia also show that AP can reduce the passage time of the oral phase and the delay time of the pharyngeal phase, as well as improve the drinking water test and related scale scores, which promotes the recovery from dysphagia after stroke ( Zhang et al, 2018 ).…”

Section: Discussionmentioning

confidence: 99%

Acupuncture Reduces the Risk of Dysphagia in Stroke Patients: A Propensity Score-Matched Cohort Study

et al. 2022

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Background: Post-stroke dysphagia (PSD) affects the quality of life in stroke patients, impairs their rehabilitation ability, and causes other complications following stroke. Currently, there is currently some understanding of PSD risk factors, but its protective factors remain largely unknown.Objective: To analyze the effects of acupuncture (AP) on dysphagia in stroke patients and explore its potential as a preventive therapy.Methods: Patients with a diagnosis of stroke from 2010 to 2019 were selected and followed until 2020, utilizing factors such as age, gender, stroke location, stroke type, and baseline comorbidity. To compare the incidence of dysphagia, equal numbers of stroke patients treated with and without AP (n = 1,809) were matched by 1:1 propensity scoring. The Cox proportional hazards model and Kaplan-Meier method were used to assess the risk of dysphagia as an outcome measure.Results: The stroke patients treated with AP had a lower risk of dysphagia after adjusting for age, gender, stroke location, stroke type, and baseline comorbidity [adjusted hazard ratio (AHR) = 0.43, 95% confidence interval = 0.37–0.49] compared with those in the non-AP cohort. AP also decreased the risk of PSD among different gender groups. The risk ratios were AHR = 0.45 and AHR = 0.33 for males and females, respectively. AP also reduced the risk for PSD among different age groups. The risk ratios were AHR = 0.20, AHR = 0.37, AHR = 0.41, and AHR = 0.45 for the 18–39, 40–59, 60–79, and >80 years-old groups. Regarding stroke types (ischemic, hemorrhagic, and mixed type), patients treated with AP had a lower risk (AHR = 0.47, 0.28 and 0.17, respectively). With respect to stroke location, the risk of PSD in AP-treated patients was decreased regardless of location: brain stem (AHR = 0.41), diencephalon (AHR = 0.13), or multiple lesions (AHR = 0.40), the risk of PSD in AP-treated patients was decreased. For all baseline comorbidities, AP attenuated the risk of dysphagia. The cumulative incidence of dysphagia was remarkably lower in the AP group than in the non-AP group (log-rank test, P = 0.000).Limitations: First, this was a single-center clinical retrospective study. Second, we did not classify the severity of stroke and dysphagia. Third, all data were extracted manually. Lastly, the sample size was relatively small. Thus, future studies with larger sample sizes are warranted to verify our findings.Conclusion: Acupuncture treatment attenuates the risk of dysphagia in stroke patients. Future research should increase the sample size and elaborate further on the details of the AP protocol.

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Decreased risk of pneumonia in stroke patients receiving acupuncture: A nationwide matched-pair retrospective cohort study

Cited by 14 publications

References 39 publications

Stroke and Pneumonia: Mechanisms, Risk Factors, Management, and Prevention

Stroke and Pneumonia: Mechanisms, Risk Factors, Management, and Prevention

Reproductive outcomes in women and men using complementary and alternative medicine treatment and not receiving artificial reproductive technology: a systematic review

Acupuncture Reduces the Risk of Dysphagia in Stroke Patients: A Propensity Score-Matched Cohort Study

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