Decreased sympathetic tone after short-term treatment with enalapril in dogs with mild chronic mitral valve disease

Chompoosan, Chayanon; Buranakarl, Chollada; Chaiyabutr, Narongsak; Chansaisakorn, Winai

doi:10.1016/j.rvsc.2014.01.006

Cited by 17 publications

(21 citation statements)

References 35 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…The non-invasive nature of data collection coupled with the availability of highly portable equipment has popularised the use of HRV in veterinary research. As such HRV has been used to evaluate cardiovascular function in disease [27,29,12], stress [23,32,1], behaviour [47], and fitness/training regimes [25] in a number of farm/companion animal species. In dogs, HRV has been compared during different physical and mental activities and in response to human interaction [6] and classical music [10].…”

Section: Introductionmentioning

confidence: 99%

‘The effect of different genres of music on the stress levels of kennelled dogs’

Bowman

Dowell

Evans

2017

Physiology & Behavior

View full text Add to dashboard Cite

Section: Introductionmentioning

confidence: 99%

‘The effect of different genres of music on the stress levels of kennelled dogs’

Bowman

Dowell

Evans

2017

Physiology & Behavior

View full text Add to dashboard Cite

“…Since implementation of computer-aided HRV analysis, it became a relatively simple and non-invasive test to examine autonomic function of the heart. Canine HRV, obtained during 24-h Holter electrocardiography, has been analyzed in both clinical and experimental settings, inter alia in dogs with mitral valve endocardiosis, tachycardiomyopathy and diabetes mellitus (Piccirillo et al 2009, Oliveira et al 2012, Pirintr et al 2012, Rasmussen et al 2012, Chompoosan et al 2014. However, analysis of HRV from 24-h electrocardiograms is challenging due to the long time of recording, unstable conditions of registration and the large number of artifacts.…”

Section: Introductionmentioning

confidence: 99%

“…The issue is important, since some therapeutic agents used in veterinary cardiology, including medications for chronic mitral valve disease (CMVD), may alter sympathetic tone, which is also reflected by changes in HRV parameters. This implies that HRV may soon become a therapeutic target in canine cardiology (Chompoosan et al 2014).…”

Section: Introductionmentioning

confidence: 99%

Short-term heart rate variability in dogs with sick sinus syndrome or chronic mitral valve disease as compared to healthy controls

Bogucki¹,

Noszczyk-Nowak²

2017

Polish Journal of Veterinary Sciences

View full text Add to dashboard Cite

Heart rate variability is an established risk factor for mortality in both healthy dogs and animals with heart failure. The aim of this study was to compare short-term heart rate variability (ST-HRV) parameters from 60-min electrocardiograms in dogs with sick sinus syndrome (SSS, n=20) or chronic mitral valve disease (CMVD, n=20) and healthy controls (n=50), and to verify the clinical application of ST-HRV analysis. The study groups differed significantly in terms of both time -and frequency-domain ST-HRV parameters. In the case of dogs with SSS and healthy controls, particularly evident differences pertained to HRV parameters linked directly to the variability of R-R intervals. Lower values of standard deviation of all R-R intervals (SDNN), standard deviation of the averaged R-R intervals for all 5-min segments (SDANN), mean of the standard deviations of all R-R intervals for all 5-min segments (SDNNI) and percentage of successive R-R intervals >50 ms (pNN50) corresponded to a decrease in parasympathetic regulation of heart rate in dogs with CMVD. These findings imply that ST-HRV may be useful for the identification of dogs with SSS and for detection of dysautonomia in animals with CMVD.

show abstract

“…Furthermore, it proved to be a useful marker of early subclinical autonomic dysfunction associated with diabetic neuropathy (Chessa et al 2002, Turker et al 2013. HRV obtained during 24-hour Holter electrocardiography was also examined in dogs, both in a clinical and experimental setting and in patients with mitral valve endocardiosis, tachycardiomyopathy and diabetes (Piccirillo et al 2009, Oliveira et al 2012, Pirintr et al 2012, Rasmussen et al 2012, Chompoosan et al 2014. Rasmussen et al (2012) found an increase in the heart rate/min (HR) and mean HR in Cavalier King Charles Spaniels with advanced chronic mitral valve disease and a decrease in most of the measured HRV parameters (total power -TP, ultra low frequency-ULF, very low frequency -VLF, % of successive NN-intervals that differ more than 50 ms -pNN50 and the square root of the mean squared differences of successive NN-intervals -RMSSD) compared to healthy dogs and those with minimal mitral regurgitation.…”

Section: Introductionmentioning

confidence: 99%

Short-term heart rate variability (HRV) in healthy dogs

Bogucki¹,

Noszczyk-Nowak²

2015

Polish Journal of Veterinary Sciences

View full text Add to dashboard Cite

Heart rate variability (HRV) is a well established mortality risk factor in both healthy dogs and those with heart failure. While the standards for short-term HRV analysis have been developed in humans, only reference values for HRV parameters determined from 24-hour ECG have been proposed in dogs. The aim of this study was to develop the reference values for short-term HRV parameters in a group of 50 healthy dogs of various breeds (age 4.86 ± 2.74 years, body weight 12.2 ± 3.88 kg). The ECG was recorded continuously for at least 180 min in a dark and quiet room. All electrocardiograms were inspected automatically and manually to eliminate atrial or ventricular premature complexes. Signals were transformed into a spectrum using the fast Fourier transform. The HRV parameters were measured at fixed times from 60-min ECG segments. The following time-domain parameters (ms) were analyzed: mean NN, SDNN, SDANN, SDNN index, rMSSD and pNN50. Moreover, frequency-domain parameters (Hz) were determined, including very low frequency (VLF), low frequency (LF) and high frequency (HF) components, total power (TP) and the LF/HF ratio. The results (means ± SD) were as follows: mean NN = 677.68 ± 126.89; SDNN = 208.86 ± 77.1; SDANN = 70.75 ± 30.9; SDNN index = 190.75 ± 76.12; rMSSD = 259 ± 120.17, pNN50 = 71.84 ± 13.96; VLF = 984.96 ± 327.7; LF = 1501.24 ± 736.32; HF = 5845.45 ± 2914.20; TP = 11065.31 ± 3866.87; LF/HF = 0.28 ± 0.11.

show abstract

Decreased sympathetic tone after short-term treatment with enalapril in dogs with mild chronic mitral valve disease

Cited by 17 publications

References 35 publications

‘The effect of different genres of music on the stress levels of kennelled dogs’

‘The effect of different genres of music on the stress levels of kennelled dogs’

Short-term heart rate variability in dogs with sick sinus syndrome or chronic mitral valve disease as compared to healthy controls

Short-term heart rate variability (HRV) in healthy dogs

Contact Info

Product

Resources

About