Decreased visual acuity is related to thinner cortex in cognitively normal adults: cross-sectional, single-center cohort study

Han, Gyule; Kim, Ji Sun; Park, Yu Hyun; Kang, Sung Hoon; Kim, Hang‐Rai; Hwangbo, Song; Chung, Tae‐Young; Shin, Hee Young; Na, Duk L.; Seo, Sang Won; Lim, Dong Hui; Kim, Hee Jin

doi:10.1186/s13195-022-01045-0

Cited by 3 publications

(2 citation statements)

References 70 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Between-group variation in measurements of cortical thickness can be confounded by variation in myelination: comparisons showing differences in cortical thickness can either be due to true differences in thickness or to differences in myelination, such that segmentation algorithms misassign voxels in the deeper layers of gray matter as white matter 42 . This ambiguity may explain why estimates of thinner cortex are linked to sometimes better 43 , 44 and sometimes worse 45 , 46 visual performance. In contrast, greater surface area is linked to greater neural count 47 , which is an important indicator of processing capacity.…”

Section: Discussionmentioning

confidence: 99%

Comparing retinotopic maps of children and adults reveals a late-stage change in how V1 samples the visual field

et al. 2023

View full text Add to dashboard Cite

Adult visual performance differs with angular location –it is better for stimuli along the horizontal than vertical, and lower than upper vertical meridian of the visual field. These perceptual asymmetries are paralleled by asymmetries in cortical surface area in primary visual cortex (V1). Children, unlike adults, have similar visual performance at the lower and upper vertical meridian. Do children have similar V1 surface area representing the upper and lower vertical meridian? Using MRI, we measure the surface area of retinotopic maps (V1-V3) in children and adults. Many features of the maps are similar between groups, including greater V1 surface area for the horizontal than vertical meridian. However, unlike adults, children have a similar amount of V1 surface area representing the lower and upper vertical meridian. These data reveal a late-stage change in V1 organization that may relate to the emergence of the visual performance asymmetry along the vertical meridian by adulthood.

show abstract

Section: Discussionmentioning

confidence: 99%

Comparing retinotopic maps of children and adults reveals a late-stage change in how V1 samples the visual field

et al. 2023

View full text Add to dashboard Cite

show abstract

“…Between-group variation in measurements of cortical thickness can be confounded by variation in myelination: comparisons showing differences in cortical thickness can either be due to true differences in thickness or to differences in myelination, such that segmentation algorithms misassign voxels in the deeper layers of gray matter as white matter 41 . This ambiguity may explain why estimates of thinner cortex are linked to sometimes better 42,43 and sometimes worse 44,45 visual performance. In contrast, greater surface area is linked to greater neural count 46 , which is an important indicator of processing capacity.…”

Section: Discussionmentioning

confidence: 99%

Comparing retinotopic maps of children and adults reveals a late-stage change in how V1 samples the visual field

Himmelberg

Tuncok

Gomez

et al. 2022

Preprint

View full text Add to dashboard Cite

Adult visual ability differs markedly with stimulus polar angle: relative to the point of fixation, visual performance is best for stimuli to the left or right, intermediate for stimuli below, and poorest for stimuli above. These polar angle asymmetries in performance are paralleled by cortical asymmetries in the visual field representation in primary visual cortex (V1). Whereas children, like adults, show better performance for stimuli along the horizontal than the vertical meridian, they show no performance difference for stimuli above vs below fixation. Is the difference in visual performance between children and adults matched by a difference in the amount of V1 surface area representing these regions? We used fMRI to measure the distribution of the cortical surface representing the visual field in children and adults. Two properties of the V1, V2, and V3 maps were mature in children -overall map surface area and variation in surface area as a function of eccentricity. Further, like adults, children had much greater V1 surface area representing the horizontal than vertical meridian. However, unlike adults, children did not have greater V1 surface area for the lower than upper vertical meridian. These data indicate a late-stage change in the architecture of V1 that may drive the emergence of a visual performance asymmetry along the vertical meridian by adulthood.

show abstract

Change in visual acuity over a 12-year period predicts cognitive decline in older adults: identifying social engagement as a potential mediator

Wilson,

Cherbuin,

Kiely

et al. 2024

Aging & Mental Health

View full text Add to dashboard Cite

Decreased visual acuity is related to thinner cortex in cognitively normal adults: cross-sectional, single-center cohort study

Cited by 3 publications

References 70 publications

Comparing retinotopic maps of children and adults reveals a late-stage change in how V1 samples the visual field

Comparing retinotopic maps of children and adults reveals a late-stage change in how V1 samples the visual field

Comparing retinotopic maps of children and adults reveals a late-stage change in how V1 samples the visual field

Change in visual acuity over a 12-year period predicts cognitive decline in older adults: identifying social engagement as a potential mediator

Contact Info

Product

Resources

About