“…For instance, previous researchers (Famiglietti et al, 2017;Mustafee et al, 2010) used DES in an outpatient clinic to evaluate and analyze the factors that impact the clinic performance in terms of patient waiting and resource utilization, while another study (Berg et al, 2013) used DES to estimate the effects of noshows on an outpatient clinic in terms of cost. In contrast, implementing DES improvement strategies within outpatient settings is often challenging because of the tremendous amount of data extracted under the conflict of interest between the stakeholders (Eldabi et al, 2007;Matta and Patterson, 2007;Robinson et al, 2012); as a result, improvements with DES tend to be focused on testing suggested new changes by the management in terms of layout, patient flow and resource flow (Demir et al, 2018;Deo et al, 2012;Harper and Gamlin, 2003;Kopach et al, 2007;Vahdat et al, 2018) or it could be focused on performing sensitivity analysis to test the impact of one or a small number of factors on the clinic performance such Lean techniques as the arrival rate, the number of resources hired and sequencing policies (Day et al, 2014;LaGanga and Lawrence, 2007;Lenin et al, 2015;Pan et al, 2015;Rau et al, 2013). In addition, some researchers applied DES to improve the clinical performance based on the effects of appointment scheduling rules and sequencing rules or other soft systems methodology on the clinical performance in terms of patient waiting and resource waiting times (Cayirli et al, 2019(Cayirli et al, , 2006Cayirli and Gunes, 2014;Yang and Cayirli, 2020).…”