Deep (aggressive) angiomyxoma of the vagina misdiagnosed as Gartner cyst: A case report

Djusad, Suskhan; Sari, Yulia Margaretta; Tjahjadi, Hartono

doi:10.1016/j.ijscr.2021.105948

Cited by 6 publications

(3 citation statements)

References 5 publications

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“…AA is a rare and slow-growing lesion that predominantly impacts the perineal and pelvic regions, mostly identified in women during their reproductive age (7). It can present variably, ranging from a painless mass next to the labia majora to non-specific symptoms such as dyspareunia, regional pain, and a feeling of pressure from the lump (5). According to the literature, the most commonly affected area is the vulva; however, the retroperitoneum and bladder can also be involved, less commonly (8).…”

Section: Discussionmentioning

confidence: 99%

“…In our case, we reported the tumor size to be approximately 10 cm in the operation field. This tumor can be confused with vulvar masses such as vulvar lipoma and vulvar leiomyomatosis, vulvar abscess, Bartholin's gland cysts, Gartner duct cyst, vaginal polyp, vaginal prolapse, mesonephric duct cyst, vaginal hernia, instantaneous levator hernia, and other soft tissue neoplasms (5,6). This locally invasive tumor might develop into other perineal structures like the vagina, rectum, and bladder (8).…”

Section: Discussionmentioning

confidence: 99%

“…AA usually appears as a vulvar polyp and is diagnosed histologically. It is also commonly confused with other conditions such as lipomas, Bartholin's gland cysts, and hernias (5,6).…”

Section: Introductionmentioning

confidence: 99%

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Massive aggressive angiomyxoma of ischioanal region with relapse: A case report

Naderzadeh,

Attarbashi,

Pourali

et al. 2024

IJRM

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Background: Aggressive angiomyxoma (AA) is a rare and slow-growing tumor in the pelvic and perineal regions that might develop into other perineal structures. It can present variably, ranging from a painless mass to non-specific symptoms such as dyspareunia. Due to the high relapse rate, extensive tumoral resection is reasonably required to prevent recurrences. It is also commonly confused with other conditions such as lipomas, Bartholin’s gland cysts, and hernias. Case Presentation: A 43-yr-old female diagnosed with AA 10 yr ago was evaluated as a consequence of the tumor recurrence. She presented rare manifestations of a giant and cystic pelvic mass involving pararectal and paravaginal tissue in front of the sacrum. Conclusion: Although AA is a rare and slow-growing tumor, close observation is recommended due to the high relapse rate. Furthermore, extensive tumoral resection and regular follow-up can reduce morbidity in these patients. Key words: Vulvar neoplasm, Perineum, Pelvic neoplasms, Recurrence.

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Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

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Massive aggressive angiomyxoma of ischioanal region with relapse: A case report

Naderzadeh,

Attarbashi,

Pourali

et al. 2024

IJRM

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Deep angiomyxoma of bladder wall

Sadashiva¹,

Vadlamani²,

Madakshira³

2024

Medical Journal Armed Forces India

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Clinicopathological characteristics and prognosis analysis of Aggressive angiomyxoma: A Retrospective Study

You

Wang

et al. 2022

Preprint

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Background: Aggressive angiomyxoma is a rare, locally invasive mesenchymal neoplasm with a high recurrence rate. However, our current research on the clinical characteristics, therapeutic strategies and prognosis of aggressive angiomyxoma is limited. This study aimed to improve the management of aggressive angiomyxoma by evaluating the clinicopathological characteristics, therapeutic strategies, and prognostic factors associated with aggressive angiomyxomas. Methods: Retrospectively analyzed the medical records of patients histopathologically diagnosed with aggressive angiomyxomas from May 2005 to January 2022. Data related to clinicopathological characteristics, therapeutic strategies, and survival time were recorded and analyzed. Survival and prognosis analyses were carried out to identify variables significantly associated with the outcomes. Results: fourteen patients were included in the study with a median follow-up of 78.8 months. Univariate Cox regression analysis identified tumor margin (P=0.012) and initial treatment site (P=0.039) as associated with disease-free survival (DFS). The Kaplan-Meier survival curve showed that tumor margin had a greater effect on the prognosis of patients. Patients with positive tumor margins had a significantly lower probability of survival with DFS than those with negative margins (HR= 3.41, CI:2.73-15.74, P=0.012). Meanwhile, we found that patients who underwent surgery in other hospitals had a lower probability of survival with DFS. This difference in survival was statistically significant (HR=1.48, CI:1.09-2.50, P=0.039). To further demonstrate the results of this study, we constructed a Nomogram model. The results showed that the tumor margin and initial treatment site had the greatest effect on patient prognosis and the greatest contribution to risk score, which confirmed the results of Kaplan-Meier survival curve analysis. Conclusion: Tumor margin and initial treatment site are closely associated with prognosis in aggressive angiomyxomas. Radical resection with negative tumor margins is the first choice of treatment for aggressive angiomyxomas. Patients with aggressive angiomyxomas should go to the comprehensive authoritative hospitals to obtain definitive diagnosis and effective treatment in in earlier stage. Furthermore, Patients with aggressive angiomyxomasrequire long-term follow-up, especially within three years after surgery.

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Deep (aggressive) angiomyxoma of the vagina misdiagnosed as Gartner cyst: A case report

Cited by 6 publications

References 5 publications

Massive aggressive angiomyxoma of ischioanal region with relapse: A case report

Massive aggressive angiomyxoma of ischioanal region with relapse: A case report

Deep angiomyxoma of bladder wall

Clinicopathological characteristics and prognosis analysis of Aggressive angiomyxoma: A Retrospective Study

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