Untreated diabetes mellitus will cause complications, and one of the diseases caused by it is Diabetic Retinopathy (DR). Machine learning is one of the methods that can be used to classify DR. Convolutional Neural Network (CNN) is a branch of machine learning that can classify images with reasonable accuracy. The Messidor dataset, which has 1,200 images, is often used as a dataset for the DR classification. Before training the model, we carried out several data preprocessing, such as labeling, resizing, cropping, separation of the green channel of images, contrast enhancement, and changing image extensions. In this paper, we proposed three methods of DR classification: Simple CNN, Le-Net, and DRnet model. The accuracy of testing of the several models of test data was 46.7%, 51.1%, and 58.3% Based on the research, we can see that DR classification must use a deep architecture so that the feature of the DR can be recognized. In this DR classification, DRnet achieved better accuracy with an average of 9.4% compared to Simple CNN and Le-Net model.