Deep eutectic solvents in liquid-phase microextraction: Contribution to green chemistry

Santos, Laize Vieira; Assis, Rosivan dos Santos de; Barreto, Jeferson Alves; Bezerra, Marcos Almeida; Novaes, Cléber Galvão; Lemos, Valfredo Azevedo

doi:10.1016/j.trac.2021.116478

Cited by 115 publications

(45 citation statements)

References 111 publications

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Section: Extraction Of Biomoleculesmentioning

confidence: 99%

“…According to the principle of green chemistry, solvents or auxiliaries can be avoided; if not, they should be non-toxic or harmless [130]. Green solvents must possess health, environmental, and safety characteristics not found in conventional solvents [130][131][132]. Solvents are often used in surplus amounts and have been categorized by their solubilization ability, flammability, toxicity, and volatility [130,132].…”

Section: Extraction Of Biomoleculesmentioning

confidence: 99%

“…Green solvents must possess health, environmental, and safety characteristics not found in conventional solvents [130][131][132]. Solvents are often used in surplus amounts and have been categorized by their solubilization ability, flammability, toxicity, and volatility [130,132]. Solvents have been used extensively in synthesis, separation, and extraction [130,131].…”

Section: Extraction Of Biomoleculesmentioning

confidence: 99%

“…Solvents are often used in surplus amounts and have been categorized by their solubilization ability, flammability, toxicity, and volatility [130,132]. Solvents have been used extensively in synthesis, separation, and extraction [130,131]. These limitations were minimized; alternative solvents such as ILs and DESs have been synthesized/prepared, characterized, and studied for their physicochemical properties [113,114,[130][131][132].…”

Section: Extraction Of Biomoleculesmentioning

confidence: 99%

“…Solvents have been used extensively in synthesis, separation, and extraction [130,131]. These limitations were minimized; alternative solvents such as ILs and DESs have been synthesized/prepared, characterized, and studied for their physicochemical properties [113,114,[130][131][132]. This search for non-toxic, environmentally compatible solvents also leads to exploring the sustainable chemical process, thus prioritizing green analytical chemistry and green chemistry [130].…”

Section: Extraction Of Biomoleculesmentioning

confidence: 99%

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Revisiting the Physicochemical Properties and Applications of Deep Eutectic Solvents

2022

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Recently, deep eutectic solvent (DES) or ionic liquid (IL) analogues have been considered as the newest green solvent, demonstrating the potential to replace harsh volatile organic solvents. DESs are mainly a combination of two compounds: hydrogen bond acceptor (HBA) and hydrogen bond donor (HBD), which have the ability to interact through extensive hydrogen bonds. A thorough understanding of their physicochemical properties is essential, given their successful applications on an industrial scale. The appropriate blend of HBA to HBD can easily fine-tune DES properties for desired applications. In this context, we have reviewed the basic information related to DESs, the two most studied physicochemical properties (density and viscosity), and their performance as a solvent in (i) drug delivery and (ii) extraction of biomolecules. A broader approach of various factors affecting their performance has been considered, giving a detailed picture of the current status of DESs in research and development.

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Section: Extraction Of Biomoleculesmentioning

confidence: 99%

Section: Extraction Of Biomoleculesmentioning

confidence: 99%

Section: Extraction Of Biomoleculesmentioning

confidence: 99%

Section: Extraction Of Biomoleculesmentioning

confidence: 99%

Section: Extraction Of Biomoleculesmentioning

confidence: 99%

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Revisiting the Physicochemical Properties and Applications of Deep Eutectic Solvents

2022

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Red beet betalains extraction process: A comprehensive review of methods, applications, and physicochemical properties

Eyshi,

Ghareaghajlou,

Afshar Mogaddam

et al. 2024

Food Science & Nutrition

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Red beet extract is rich in bioactive compounds and possesses health‐promoting properties. Moreover, the stability of red beet extract over a broad acidic pH range has given them great potential in developing new functional foods and drinks. The choice of extraction solvent and methodology significantly influences the efficiency of betalain extraction from plant vacuoles. Although the conventional solvent extraction method has been widely employed for betalain extraction, recent innovations have introduced alternative methods that offer advantages, such as reduced solvent consumption, energy efficiency, and minimized exposure to high temperatures. This paper aims to summarize the current knowledge about conventional and novel extraction methods, applications, biological activities, and purification of red beet betalains. Furthermore, the physicochemical properties of betalain‐rich extract of red beet and associated safety considerations have been investigated.

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Recent overview of microextraction of metal ions and pharmaceuticals by solidified floating organic drop microextraction techniques

Kumar,

Satapathy,

Kurmi

et al. 2024

Separation Science Plus

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This work presents a comprehensive overview of solidified floating organic drop microextraction, with a particular emphasis on its applications in the analysis of heavy metal ions and different pharmaceutical compounds by sample pretreatment, complexation, and their identification by various analytical techniques. Here, we discussed basic principles, procedures, applications of the technique, and effects of different variables like pH, temperature, stirring rate, extraction time, salts addition, extraction solvent and extraction volume, centrifugation speed, and, vortex time on preconcentration. In brief, the review summarises the various modes of solidified floating organic drop microextraction such as dispersive liquid‐liquid microextraction, ultrasound‐assisted, air‐assisted liquid‐liquid microextraction, and vortex‐assisted solidified floating organic drop microextraction. this review covers the methods combined with analytical techniques such as inductively coupled plasma‐optical emission spectrometry, electrothermal atomic absorption spectrometry, flame atomic absorption spectroscopy, graphite furnace atomic absorption spectrometry, electrothermal vaporization inductively coupled plasma mass spectrometry, high‐performance liquid chromatography, and gas chromatography/mass spectrometry. among these, the incorporation of ultrasonic, vortex, and air agitation improves the dispersion mechanism. The coupling of solidified floating organic drop microextraction with other techniques enhances the selectivity and efficiency of the preconcentration procedure. This review provides a potential overview of the fundamental principles, advancements in various modes, influencing factors, and applications of solidified floating organic drop microextraction, showing its potential for advancements in sample preparation and analytical methodologies across various domains.

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Deep eutectic solvents in liquid-phase microextraction: Contribution to green chemistry

Cited by 115 publications

References 111 publications

Revisiting the Physicochemical Properties and Applications of Deep Eutectic Solvents

Revisiting the Physicochemical Properties and Applications of Deep Eutectic Solvents

Red beet betalains extraction process: A comprehensive review of methods, applications, and physicochemical properties

Recent overview of microextraction of metal ions and pharmaceuticals by solidified floating organic drop microextraction techniques

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