Deep Negative T Waves and Abnormal Cardiac Sympathetic Image (123I-MIBG) After the Great Hanshin Earthquake of 1995

Yagi, Hiroshi; Hanaoka, Junichi; Funakoshi, Takahiro; Iwahashi, Masanori; Takeuchi, Motoshi; Saito, Komei; Kawashima, Seinosuke; Yokoyama, Mitsuhiro

doi:10.1016/s0002-9629(15)41699-4

Cited by 9 publications

(8 citation statements)

References 17 publications

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“…[18][19][20][21] In contrast to ACS, 'Takotsubo' cardiomyopathy has characteristic clinical findings, such as female predominance, infrequent history of coronary artery disease, and relatively favorable outcome. [1][2][3][4][5][6] However, in the acute stage it is difficult to definitely differentiate 'Takotsubo' cardiomyopathy from ACS by 12-lead ECG or other non-invasive methods.…”

Section: Acs and 'Takotsubo' Cardiomyopathy After The Earthquakementioning

confidence: 99%

“…7 The results of coronary angiography were not reported in 2 previous studies, 20,21 and in the others a small number of patients underwent coronary angiography for a diagnosis of acute myocardial infarction after an earthquake, but some of them were reported to have no significant stenosis. 18,19 Those cases may have been 'Takotsubo' cardiomyopathy.…”

Section: Acs and 'Takotsubo' Cardiomyopathy After The Earthquakementioning

confidence: 99%

See 1 more Smart Citation

Increased Incidence of Transient Left Ventricular Apical Ballooning (So-Called Takotsubo' Cardiomyopathy) After the Mid-Niigata Prefecture Earthquake

Sato¹,

Fujita²,

Saito³

et al. 2006

Circ J

112

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Section: Acs and 'Takotsubo' Cardiomyopathy After The Earthquakementioning

confidence: 99%

Section: Acs and 'Takotsubo' Cardiomyopathy After The Earthquakementioning

confidence: 99%

Increased Incidence of Transient Left Ventricular Apical Ballooning (So-Called Takotsubo' Cardiomyopathy) After the Mid-Niigata Prefecture Earthquake

Sato¹,

Fujita²,

Saito³

et al. 2006

Circ J

112

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“…In Japan, after the Hanshin -Awaji earthquake, Yamabe et al [30] observed an increase in the incidence of patients with deep negative T waves. In a rat model, activation of cardiac adrenoceptors by psychological stress causes similar ECG changes [24,31,32].…”

Section: Efmentioning

confidence: 99%

Reversible ventricular dysfunction takotsubo cardiomyopathy

Akashi

Musha

Kida

et al. 2005

European J of Heart Fail

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Background: Recently, many cardiologists have recognized the existence of a rapidly reversible form of heart failure of unknown origin characterized by a takotsubo-shaped, dyskinetic left ventricle on left ventriculography. Aim: To determine the detailed clinical features of takotsubo cardiomyopathy. Methods: Thirteen elderly patients (11 women and 2 men with a mean age of 75.3 years) who had normal coronary arteries and takotsubolike left ventricular dysfunction were prospectively enrolled in this study. Results: Cardiac enzymes did not increase significantly, but the mean plasma norepinephrine level was very high on admission (0.98 Ag/l). Coronary angiography revealed normal coronary arteries in all patients, but left ventriculography showed apical akinesis combined with basal hyperkinesis, i.e., a takotsubo (Japanese octopus fishing pot)-shaped ventricle. Left ventricular wall motion normalized within a mean of 16.9 hospital days in 12 patients, but 1 patient died of acute renal failure on hospital day 7. Cardiac events did not recur during a follow-up period of 0.5 to 5 years. Conclusion: Takotsubo cardiomyopathy seems to be a new type of acute heart failure, which generally has a good prognosis and does not recur. Myocardial damage by catecholamine overload, adrenoceptor hypersensitivity, and changes of catecholamine dynamics due to stress may cause this condition.

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“…Mismatches between scintigraphy-imaged myocardial sympathetic nerve function and myocardial blood flow have been found in patients with traumatic stress. 22 Such cardiac hypersensitivity to catecholamines is not necessarily related to myocardial ischemia; therefore, coronary microvascular inflammation and microneuropathy limited to the heart are unlikely causes of takotsubo cardiomyopathy.…”

Section: Diastole Systolementioning

confidence: 99%